Detalhe da pesquisa
1.
A Landscape of Pharmacogenomic Interactions in Cancer.
Cell
; 166(3): 740-754, 2016 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27397505
2.
Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors.
Cancer Cell
; 7(4): 325-36, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15837622
3.
Biochemical and transcriptional profiling to triage additional activities in a series of IGF-1R/IR inhibitors.
Bioorg Med Chem
; 20(6): 1961-72, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22137930
4.
Deep learning reveals predictive sequence concepts within immune repertoires to immunotherapy.
Sci Adv
; 8(37): eabq5089, 2022 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36112691
5.
Soluble PD-L1 as an early marker of progressive disease on nivolumab.
J Immunother Cancer
; 10(2)2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35131863
6.
Biomarker analysis from CheckMate 214: nivolumab plus ipilimumab versus sunitinib in renal cell carcinoma.
J Immunother Cancer
; 10(3)2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35304405
7.
Molecular correlates of response to nivolumab at baseline and on treatment in patients with RCC.
J Immunother Cancer
; 9(3)2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33658305
8.
Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4.
Clin Cancer Res
; 27(19): 5389-5400, 2021 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34230026
9.
Integrative molecular characterization of sarcomatoid and rhabdoid renal cell carcinoma.
Nat Commun
; 12(1): 808, 2021 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33547292
10.
Transcriptional profiling of the dose response: a more powerful approach for characterizing drug activities.
PLoS Comput Biol
; 5(9): e1000512, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19763178
11.
Integrative Tumor and Immune Cell Multi-omic Analyses Predict Response to Immune Checkpoint Blockade in Melanoma.
Cell Rep Med
; 1(8): 100139, 2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33294860
12.
Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma.
Nat Med
; 26(6): 909-918, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32472114
13.
Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma.
Cancer Cell
; 38(4): 500-515.e3, 2020 10 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-32916126
14.
Chemical genetics reveals an RGS/G-protein role in the action of a compound.
PLoS Genet
; 2(4): e57, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16683034
15.
Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors.
Mol Cancer Ther
; 7(11): 3490-8, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19001433
16.
Construction of a reference gene association network from multiple profiling data: application to data analysis.
Bioinformatics
; 23(20): 2716-24, 2007 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17846039
17.
Genome-wide association analysis identifies genetic correlates of immune infiltrates in solid tumors.
PLoS One
; 12(7): e0179726, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28749946
18.
Immunomodulatory Activity of Nivolumab in Metastatic Renal Cell Carcinoma.
Clin Cancer Res
; 22(22): 5461-5471, 2016 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27169994
19.
Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma.
Cancer Cell
; 39(1): 122, 2021 Jan 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33306984
20.
Model systems in drug discovery: chemical genetics meets genomics.
Pharmacol Ther
; 99(2): 183-220, 2003 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-12888112