Detalhe da pesquisa
1.
iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I.
Cell Mol Life Sci
; 81(1): 163, 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38570362
2.
New isoxazolidinyl-based N-alkylethanolamines as new activators of human brain carbonic anhydrases.
J Enzyme Inhib Med Chem
; 38(1): 2164574, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36630083
3.
Identification of N-Acyl Hydrazones as New Non-Zinc-Binding MMP-13 Inhibitors by Structure-Based Virtual Screening Studies and Chemical Optimization.
Int J Mol Sci
; 24(13)2023 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37446276
4.
Bacterial Zinc Metalloenzyme Inhibitors: Recent Advances and Future Perspectives.
Molecules
; 28(11)2023 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37298854
5.
Inhibitors of ADAM10 reduce Hodgkin lymphoma cell growth in 3D microenvironments and enhance brentuximab-vedotin effect.
Haematologica
; 107(4): 909-920, 2022 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34109776
6.
The metalloproteinase ADAM10 requires its activity to sustain surface expression.
Cell Mol Life Sci
; 78(2): 715-732, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32372373
7.
Activation of carbonic anhydrases from human brain by amino alcohol oxime ethers: towards human carbonic anhydrase VII selective activators.
J Enzyme Inhib Med Chem
; 36(1): 48-57, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33103482
8.
Development of a fluorogenic ADAMTS-7 substrate.
J Enzyme Inhib Med Chem
; 36(1): 2160-2169, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34587841
9.
Identification of histone deacetylase inhibitors with (arylidene)aminoxy scaffold active in uveal melanoma cell lines.
J Enzyme Inhib Med Chem
; 36(1): 34-47, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33100043
10.
Strategies to Target ADAM17 in Disease: From its Discovery to the iRhom Revolution.
Molecules
; 26(4)2021 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33579029
11.
Identification of Broad-Spectrum MMP Inhibitors by Virtual Screening.
Molecules
; 26(15)2021 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34361703
12.
Deficient Natural Killer Cell NKp30-Mediated Function and Altered NCR3 Splice Variants in Hepatocellular Carcinoma.
Hepatology
; 69(3): 1165-1179, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30153337
13.
Monoaryl derivatives as transthyretin fibril formation inhibitors: Design, synthesis, biological evaluation and structural analysis.
Bioorg Med Chem
; 28(18): 115673, 2020 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32828431
14.
An overview of carbohydrate-based carbonic anhydrase inhibitors.
J Enzyme Inhib Med Chem
; 35(1): 1906-1922, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-33078634
15.
Metalloprotease inhibitor profiles of human ADAM8 in vitro and in cell-based assays.
Biol Chem
; 400(6): 801-810, 2019 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30738011
16.
The metalloprotease ADAM10 (a disintegrin and metalloprotease 10) undergoes rapid, postlysis autocatalytic degradation.
FASEB J
; 32(7): 3560-3573, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29430990
17.
Design, synthesis and biological evaluation of bifunctional inhibitors of membrane type 1 matrix metalloproteinase (MT1-MMP).
Bioorg Med Chem
; 27(1): 196-207, 2019 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30522899
18.
Matrix metalloproteinase-12 inhibitors: synthesis, structure-activity relationships and intestinal absorption of novel sugar-based biphenylsulfonamide carboxylates.
Bioorg Med Chem
; 26(22): 5804-5815, 2018 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30429099
19.
Hepatitis C virus-induced NK cell activation causes metzincin-mediated CD16 cleavage and impaired antibody-dependent cytotoxicity.
J Hepatol
; 66(6): 1130-1137, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28192188
20.
N-(Aroyl)-N-(arylmethyloxy)-α-alanines: Selective inhibitors of aldose reductase.
Bioorg Med Chem
; 25(12): 3068-3076, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28392277