Detalhe da pesquisa
1.
New insights into the structure and function of the complex between the Escherichia coli Hsp70, DnaK, and its nucleotide-exchange factor, GrpE.
J Biol Chem
; 300(1): 105574, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38110031
2.
Slow Protein Dynamics Elicits New Enzymatic Functions by Means of Epistatic Interactions.
Mol Biol Evol
; 39(10)2022 10 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36136729
3.
Rational Design of Benzobisheterocycle Metallo-ß-Lactamase Inhibitors: A Tricyclic Scaffold Enhances Potency against Target Enzymes.
J Med Chem
; 67(5): 3795-3812, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38373290
4.
Correction: 2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-ß-lactamases.
Chem Sci
; 14(34): 9226, 2023 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37655038
5.
The urgent need for metallo-ß-lactamase inhibitors: an unattended global threat.
Lancet Infect Dis
; 22(1): e28-e34, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34246322
6.
2-Mercaptomethyl-thiazolidines use conserved aromatic-S interactions to achieve broad-range inhibition of metallo-ß-lactamases.
Chem Sci
; 12(8): 2898-2908, 2021 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34164056
7.
2-Mercaptomethyl Thiazolidines (MMTZs) Inhibit All Metallo-ß-Lactamase Classes by Maintaining a Conserved Binding Mode.
ACS Infect Dis
; 7(9): 2697-2706, 2021 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34355567
8.
Metallo-ß-Lactamase Inhibitors Inspired on Snapshots from the Catalytic Mechanism.
Biomolecules
; 10(6)2020 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32503337