Detalhe da pesquisa
1.
Crizanlizumab for the Prevention of Pain Crises in Sickle Cell Disease.
N Engl J Med
; 376(5): 429-439, 2017 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27959701
2.
Complement regulator CD59 protects against atherosclerosis by restricting the formation of complement membrane attack complex.
Circ Res
; 104(4): 550-8, 2009 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19131645
3.
Anti-GD1a antibodies activate complement and calpain to injure distal motor nodes of Ranvier in mice.
Brain
; 133(Pt 7): 1944-60, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20513658
4.
Effect of eculizumab on haemolysis-associated nitric oxide depletion, dyspnoea, and measures of pulmonary hypertension in patients with paroxysmal nocturnal haemoglobinuria.
Br J Haematol
; 149(3): 414-25, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20230403
5.
The management of pregnancy in paroxysmal nocturnal haemoglobinuria on long term eculizumab.
Br J Haematol
; 149(3): 446-50, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20151973
6.
Eculizumab prevents intravascular hemolysis in patients with paroxysmal nocturnal hemoglobinuria and unmasks low-level extravascular hemolysis occurring through C3 opsonization.
Haematologica
; 95(4): 567-73, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20145265
7.
Long-term effect of the complement inhibitor eculizumab on kidney function in patients with paroxysmal nocturnal hemoglobinuria.
Am J Hematol
; 85(8): 553-9, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20658586
8.
Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria.
Nat Biotechnol
; 25(11): 1256-64, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17989688
9.
The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria.
N Engl J Med
; 355(12): 1233-43, 2006 Sep 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16990386
10.
Successful liver transplantation for Budd-Chiari syndrome in a patient with paroxysmal nocturnal hemoglobinuria treated with the anti-complement antibody eculizumab.
Liver Transpl
; 15(5): 540-3, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19399743
11.
Eculizumab prevents anti-ganglioside antibody-mediated neuropathy in a murine model.
Brain
; 131(Pt 5): 1197-208, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18184663
12.
Eculizumab, a terminal complement inhibitor, improves anaemia in patients with paroxysmal nocturnal haemoglobinuria.
Br J Haematol
; 142(2): 263-72, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18503589
13.
Eculizumab for congenital atypical hemolytic-uremic syndrome.
N Engl J Med
; 360(5): 544-6, 2009 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-19179329
14.
Effect of eculizumab on hemolysis and transfusion requirements in patients with paroxysmal nocturnal hemoglobinuria.
N Engl J Med
; 350(6): 552-9, 2004 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-14762182
15.
The effects of the fibrin-derived peptide Bbeta(15-42) in acute and chronic rodent models of myocardial ischemia-reperfusion.
Shock
; 27(6): 631-7, 2007 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-17505302
16.
Long-term efficacy of the complement inhibitor eculizumab in cold agglutinin disease.
Blood
; 113(16): 3885-6, 2009 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19372265
17.
Prevention of acute vascular rejection by a functionally blocking anti-C5 monoclonal antibody combined with cyclosporine.
Transplantation
; 79(9): 1121-7, 2005 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15880054
18.
Improvement in the symptoms of smooth muscle dystonia during eculizumab therapy in paroxysmal nocturnal hemoglobinuria.
Haematologica
; 90(12 Suppl): ECR40, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16464755
19.
The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease.
JAMA
; 293(13): 1653-62, 2005 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15811985
20.
Multicenter phase 3 study of the complement inhibitor eculizumab for the treatment of patients with paroxysmal nocturnal hemoglobinuria.
Blood
; 111(4): 1840-7, 2008 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18055865