High-resolution MR imaging for dental impressions: a feasibility study.

OBJECTIVES: Magnetic resonance imaging is an emerging technology in dental medicine. While low-resolution MRI has especially provided means to examine the temporomandibular joint due to its anatomic inaccessibility, it was the goal of this study to assess whether high-resolution MRI is capable of delivering a dataset sufficiently precise enough to serve as digital impression of human teeth. MATERIALS AND METHODS: An informed and consenting patient in need of dental restoration with fixed partial dentures was chosen as subject. Two prepared teeth were measured using MRI and the dataset subjected to mathematical processing before Fourier transformation. After reconstruction, a 3D file was generated which was fed into an existing industry standard CAD/CAM process. RESULTS: A framework for a fixed dental prosthesis was digitally modeled and manufactured by laser-sintering. The fit in situ was found to be acceptable by current clinical standards, which allowed permanent placement of the fixed prosthesis. CONCLUSIONS: Using a clinical whole-body MR scanner with the addition of custom add-on hardware, contrast enhancement, and data post-processing, resolution and signal-to-noise ratio were sufficiently achieved to allow fabrication of a dental restoration in an acquisition time comparable to the setting time of common dental impression materials. Furthermore, the measurement was well tolerated. CLINICAL RELEVANCE: The herein described method can be regarded as proof of principle that MRI is a promising option for digital impressions when fixed partial dentures are required.

Diagnosis of dental abnormalities in children using 3-dimensional magnetic resonance imaging.

PURPOSE: To assess the feasibility of magnetic resonance imaging (MRI) of dental abnormalities in children. MATERIALS AND METHODS: The study included 16 patients (mean age, 10.8 yr) prospectively selected from 1,500 orthodontic patients. The selected patients included 3 with a mesiodens, 9 with supernumerary teeth other than a mesiodens, 1 with gemination, 1 with dilacerations, 1 with transmigration, and 1 with transposition. Three-dimensional (3D) images were acquired on a 1.5-T MRI scanner using a 3D turbo spin echo pulse sequence with a voxel size of 0.8 × 0.8 × 1 mm. The measurement time was 4 to 5 minutes. RESULTS: Using natural MRI contrast, the teeth, dental pulp, mandibular canal, and cortical bone could be clearly delineated. The position and shape of malformed teeth could be assessed in all 3 spatial dimensions. CONCLUSION: MRI was found to be a well-tolerated imaging modality for the diagnosis of dental abnormalities in children and for orthodontic treatment and surgical planning. Compared with conventional radiography, dental MRI provides the advantage of 3-dimensionality and complete elimination of ionizing radiation, which is particularly relevant for repeated examinations in children.

On precise localization of boundaries between extended uniform objects in MRI: tooth imaging as an example.

OBJECT: The purpose of this study was to investigate the achievable precision of localization of boundaries between extended uniform objects in MRI and to study the effect of zero-filling on reaching it. MATERIALS AND METHODS: A theoretical model of an object boundary in the presence of noise was introduced, and the error of localization was derived. The effect of zero-filling on reaching the achievable precision was assessed by computer simulations and experimentally on an extracted tooth in a signal-giving medium. RESULTS: With the help of the theoretical model, the achievable precision of localization of boundaries between two uniform extended objects was shown to surpass the nominal resolution by a factor equal to the contrast-to-noise ratio. In the simulations and phantom experiments, zero-filling followed by image segmentation allowed for approaching the theoretical value. As an application example, an MRI-based dental impression was performed in vivo, and a bridge was produced and permanently fixed to the volunteer's teeth. CONCLUSION: This work demonstrates that in an MRI experiment, the achievable precision of localization of object boundaries is not limited to the nominal resolution and can surpass it by an order of magnitude. Zero-filling is a simple and effective method of reaching it.

High-resolution 3D magnetic resonance imaging and quantification of carious lesions and dental pulp in vivo.

OBJECTIVE: The purpose of the study was to assess the feasibility of MRI of three-dimensional visualization and quantification of carious lesions, as well as measurement of the distance between the lesion and dental pulp in vivo. MATERIALS AND METHODS: High-resolution 3D MRI was performed to measure seven carious lesions in vivo using gelatinous gadolinium-based oral contrast medium in combination with an intraoral radio frequency receiver coil on a clinical 1.5 T MRI scanner. Extension of the carious lesion in three spatial dimensions and the minimum distance between the lesion and dental pulp were quantified. When possible, the result was compared to an X-ray projection and an impression of the lesion taken using a plastic impression material before and after dental treatment. RESULTS: Carious lesions, including pit and fissure, approximal lesions, and occult dentin caries, could be visualized due to the MRI signal rise in the porous affected dentin. The minimum distance between the carious lesion and dental pulp could be determined in all cases. CONCLUSION: The results presented demonstrate the feasibility of high-resolution dental MRI to three-dimensionally visualize and quantify carious lesions, including approximal and occult caries lesions, and measure the minimum distance to the dental pulp.

A new design for post and core restorations implementing positive locking.

The design of a post and core restoration is a trade-off between a series of requirements to achieve stability of the post itself, the surrounding root dentine and the joint between tooth and post, while maintaining a sufficient apical seal of the remaining root canal filling. Post and core restoration systems come in a variety of different designs and dimensions, where each has its specific strength and weakness. With the exception of threaded versions, posts normally rely on either chemical and/or frictional locking between the post and the remaining root. Failure due to fatigue of the joint or root fracture due to overloading of the dentine is a frequent failure mode, especially for posts anchoring removable prostheses. Perforation of the root in an attempt to maximize the post length is a main cause for failure, too. A new design is proposed which uses a short but large diameter post. The risk of decementation is reduced by positive locking. A cavity with an undercut is prepared into the root, into which the post is fitted. Once joined, the post cannot be separated from the tooth without destruction of either the root or the post. The principle of the new design uses preparation tools and a post which is spread at the bottom. A cylindrically prepared hole is re-shaped to a defined inverse taper with the wider diameter at the bottom of the hole. A cylindrical post is inserted and spread at the bottom to a matching shape after placement. A first in vitro test of the stability showed that the positive locking provides at least as good extraction resistance as conventional post without the critical reliance on the luting/bonding agent.

Effect of load angulation and crown shape on forces acting on post and core restored teeth: an in vitro study.

To assess the usefulness of different post and core materials and systems, in vitro testing of fracture strength and fatigue resistance is a useful tool. However, the literature does not present coherent results as to which system can withstand the highest loads. With a geometrical model, the effects of load angulation and contact point location on the generated forces were calculated. To validate the mathematical model, a set of measurements was performed with a set-up that made it possible to measure the critical forces on a post and core restoration. A high level of correlation between the predictions of the model and the measurements was found. It was shown that the resulting forces are strongly dependent on the precise design of the test set-up and results from different geometries cannot be compared directly. Very strong sensitivity to small misalignment was found, all of which serves to explain the large differences in the literature.

Mechanical loading of orthodontic miniscrews - significance and problems: an experimental study.

Orthodontic miniscrews are exposed to three mechanical loading phases during clinical use: torsional loading upon insertion, flexural loading during anchorage function, and torsional loading upon removal. The aim of this study was to simulate clinical loading conditions for different types of orthodontic miniscrews in vitro to quantify the effects of combined torsional and bending stress. Various orthodontic miniscrew systems (Lomas, Dual-top, Aarhus anchorage, Tomas-pin and T.I.T.A.N.-pin) comprising 10 samples each were subjected to the following loading sequences in vitro: a torsional load corresponding to manual insertion with limited torque; and flexural loading at two different insertion depths. For all screw systems with torsional pre-loading (simulating insertion), subsequent flexural loading (simulating anchorage) yielded permanent deformations of approximately 0.15-0.25 mm, depending on the insertion depth. Since EDX analysis revealed comparable elemental compositions for the different screw systems, the differences in mechanical properties are attributed to screw design. Torsional loading during screw insertion may cause premature mechanical weakening and needs to be minimized. Unless fully inserted, screws show pronounced plastic deformation and hence fracture risk under subsequent flexural loading.

Failure analysis of a new post-and-core restoration system using the finite element method.

Human teeth with substantial coronal defects are subject to reconstruction by means of post-and-core restorations. Typically, such a restoration comprises a slightly cylindrical post onto which an abutment of varying shape, depending on the designated restoration, is attached. As clinical results are not satisfactory to date, a new post-and-core design which makes use of positive locking (rather than relying on chemical bonding agents for retention in the residual root) was proposed. Using proprietary burs, an inversely conical hole is machined into the root, into which the prefabricated post-and-core restoration is inserted. This part can be spread at the bottom to match the cavity's undercut form, resulting in a positive lock which can only be separated by destruction of root, restoration or both. Another key feature of this system is a ring/groove geometry which is able to absorb the wedging forces created by said spreading and the stress of loading of the restoration which arises from mascatory forces. To assess the properties, especially in terms of the stress imposed on the remaining tooth at highest possible loading, both finite element simulations and in vitro failure tests were performed and the findings compared. The results suggest that the parameters of the finite element simulations are in good agreement with reality. As calculated and measured force levels immediately before failure of the restoration are high, the introduced new geometry has significant advantages over the classical restoration.

The influence of the root cross-section on the stress distribution in teeth restored with a positive-locking post and core design: a finite element study.

Human teeth with substantial coronal defects are subject to reconstruction by means of post and core restorations. Typically, such a restoration comprises a slightly cylindrical post onto which an abutment of varying shape, depending on the designated restoration, is attached. As clinical results are not satisfactory to date, we proposed a new proprietary post and core design which makes use of positive locking. As this prefabricated system is not customised to an individual root's cross-sectional geometry (usually oval), a varying amount of radicular dentin is left in periphery of the core's outer edge. The aim of this study was to assess the implications of this fact, i.e., whether the root has to endure higher overall stress levels which ultimately may lead to failure of one of the components involved. A series of finite element simulations were performed to evaluate stress and strain on the system, in which the proposed post and core was embedded into a virtual dentin cylinder of different diameters, ranging from flush mounting of the restoration to a dentin excess of 4 mm, and subsequently loaded with forces with two angles of attack (90 degrees and 130 degrees ). The results show that flush mounting yields an agreeable stress and strain distribution within the radicular dentin, but overall stress levels drop significantly with an excess of 0.5 mm of surrounding dentin. More than 1 mm excess was not found to have profound positive effects.

A michigan-type occlusal splint with spring-loaded mandibular protrusion functionality for treatment of anterior disk dislocation with reduction.

For treatment of temporomandibular disorders Michigan-type splints are frequently used, as are mandibular advancement appliances for patients diagnosed with anterior disk dislocation. As both types show good results, the combination of these two mechanisms into one bimaxillary appliance was tested on eight patients where splint therapy had brought reduction but not complete elimination of the symptoms. An existing maxillary Michigan splint was modified so that advancement springs could be fitted and the generated forces were transmitted to a mandibular retainer, which did not interfere with the function of the splint. Treatment progress was monitored with computerized axiography and in all cases the axiographic tracings after the bimaxillary treatment showed no pattern indicative of disk dislocation under normal jaw movements. Myofascial pain symptoms, already improved by the pre-treatment with the Michigan splint, were found to be reduced further or eliminated completely. The approach of retrofitting a Michigan splint with the springs allowed for a versatile appliance, which required no occlusal alteration to the finely adapted splint but could as easily be brought back to the simple splint-functionality either for daytime use or for a period of stabilization of the result after successful treatment. Compliance was found to be very good and the short treatment period, together with the small force levels did not produce any detectable dental side effects.

Correlation of MRT imaging with real-time axiography of TMJ clicks.

There is a series of tools useful for gathering diagnostic information on patients with temporomandibular joint disorders. Tracings of the joint movement (axiography) provide useful information about the motion of the joints. Since the availability of electronic axiographic tracers, the movement of the condyles can be resolved with high resolution both in space and in time. In order to obtain information about the anatomical relation of the joint surfaces and the disc, magnetic resonance tomography imaging (MRI) is routinely carried out. It is common practice to take MR images of the joints with the mouth closed and fully open. In order to correlate the MR images with the axiographic tracings, a series of images can provide much more information. In this study we examined patients with distinct temporomandibular joint (TMJ) clicks. In one case, the click occurs once a day, while in the other case the click happens every time the mouth is opened. In order to obtain information about both motion and anatomical relation of the TMJ at and around the position where the clicks occur, we recorded a series of MRI scans with the mouth gradually opened and before and after joint clicks. Real-time axiographic tracings during the click were taken with an optimized system where the polar moments were reduced as much as possible to follow the movement during the click. These tracings were correlated with the MRI scans to determine the exact internal conditions of the TMJ and the changes during the click. In particular cases, the additional information provided by this procedure can be useful in deciding whether and which therapeutic intervention is advisable.

Effects of centric relation prematurities of the frontal teeth.

Centric relation prematurities of frontal teeth are frequently found with patients who have severe orthodontic anomalies or received extensive restorative treatment. They can cause a range of symptoms ranging from loosening of the teeth to temporomandibular disorders (TMD). The objective of this work has been to derive a mathematical description of the mandibular and periodontal forces generated by anterior prematurities for different incisor relations. In order to quantify the effect of contact area (location and inclination) and the tooth inclination, a two-dimensional mathematical approach was used. Vectorisation of the forces and bending moments makes it possible to predict under which conditions the load increase mainly affecting the anterior teeth can and may cause localized pain and eventually loosening and flaring/crowding of the upper/lower incisors and under which conditions the temporomandibular joint will suffer a large increase in retrusive force, which potentially leads to TMD. For 10 patients with anterior prematurities, analysis of the incisor relation was carried out. For all cases the conclusions drawn from the mathematical model were in full agreement with the reported symptoms, which could be successfully treated.

High isotropic resolution magnetic resonance imaging of the mandibular canal at 1.5 T: a comparison of gradient and spin echo sequences.

OBJECTIVES: The precision of localizing the mandibular canal prior to surgical intervention depends on the achievable resolution, whereas identification of the nerve depends on the image contrast. In our study, we developed new protocols based on gradient and spin echo sequences. The results from both sequences were quantitatively compared for their agreement to identify the most suitable approach. METHODS: By limiting the field of view to one side of the mandible, three-dimensional acquisitions with T1 weighted gradient and spin echo sequences were performed with 0.5 × 0.5 × 0.5 mm3 resolution within 6.5 min covering the mandibular canal from the mandibular to the mental foramen. Aliasing artefacts were suppressed by different techniques. A manual segmentation of the mandibular canal from seven healthy volunteers was performed on this section by three different observers. The surface distance of the segmented volumes was computed between both sequences as well as between the different observers as a measure of equality. RESULTS: The quantitative comparison of the segmentation resulted in an average surface distance of 0.26 ± 0.05 mm between both sequences and an interobserver difference of 0.26 ± 0.08 mm for gradient and 0.29 ± 0.07 mm for spin echo data. By repeated evaluation, a difference of 0.15 ± 0.02 mm for gradient and 0.18 ± 0.03 mm for spin echo data was observed, indicating a slightly higher variability for spin echo images. CONCLUSIONS: Both sequences can be used to achieve high-resolution images with good contrast and can be used for precise localization of the mandibular canal. Despite a slightly increased difference for the spin echo data, the advantage of an easy and robust setup remains.

Functional 3-D analysis of patients with unilateral cleft of lip, alveolus and palate (UCLAP) following lip repair.

INTRODUCTION: Particular importance is attached to lip repair cleft surgery, as numerous functional and aesthetic aspects have to be taken into account simultaneously. Spatial assessment of function and depiction of dynamic deviations is reasonable for describing surgical outcome in addition to long standing static analysis. This study aimed at 3D analysis of the oral area after reconstruction in patients with unilateral cleft lip, alveolus and palate. PATIENTS AND METHODS: Twelve patients with unilateral cleft lip, alveolus and palate who underwent surgery according to Tennison-Randall were enrolled in this study. Soft tissue dynamics was analysed during passive stretching and active contraction of the lips, and photogrammetry was used for comparing relative changes of length and displacement vectors. The spatial coordinates of surgically significant and reproducible landmarks along the red-white lip junction were analyzed. RESULTS: Static analysis of the lips revealed a good result with far-reaching symmetry in all cases. Regarding dynamic behaviour, two groups could be distinguished showing clear differences of passive distension and contraction behaviour. CONCLUSION: Despite nominally identical surgical techniques and comparable static-morphological outcomes, dynamic analysis revealed differences pointing to a need for optimization.

Measurement of tooth and implant mobility under physiological loading conditions.

In vivo measurement of the mobility of teeth under physiological loading has been subject of research for years. Comparing the deflection under load of dental implants with teeth provides valuable input for designing restorations spanning both teeth and implants. Physiological force rise time of about 50-100 ms and displacement of 10-100 µm requires high spatial and temporal resolution of the measurement set-up. Using an optical system attached to the teeth/implants to be measured and a light source attached to a point of reference, displacement of teeth and implants under axial and lateral loading was measured on a series of volunteers. Axial displacement of teeth shows strong time dependence consistent with (hydraulic) damping not observed for lateral loads. Displacement under lateral loading was found to be about one order of magnitude higher than under axial load. For dental implants elastic deflection was observed in axial and lateral direction without measurable influence of the load rise time. For purely axial loading, dental implants and teeth show similar deflection under physiological force rise time but for lateral loading the considerably difference between teeth and implant may put some restrictions on the construction of tooth-implant-bridges, especially for teeth in the anterior region.

Effect of occlusal morphology on the accuracy of bite force measurements using thin film transducers.

PURPOSE: Occlusal transducer foils using piezoelectricity or pressure-dependent electric resistance are potential candidates for a measurement system for both absolute levels and changes in bite force. This preliminary in vitro study evaluated the possible usefulness of such transducer foils in the assessment of occlusal forces in centric occlusion. MATERIALS AND METHODS: Piezoelectric force transducer foils 33 microm thick were placed between pairs of teeth with the dentition in centric occlusion. Occlusal forces were recorded in five patients, who were instructed to bite as hard as possible for about 1 second. Acrylic resin casts of each pair of antagonistic teeth were aligned with the help of interocclusal records. The casts were mounted in a jig, where a defined load could be applied. The ratio of applied force and measured sensor signal permitted a set of calibration factors. RESULTS: A correction factor for each pair of teeth helped determine the ratio by which measured occlusal force exceeded actual tooth load. Differences in occlusal morphology gave rise to a wide span of correction factors (1.01 to 2.80). Steep cusp angles resulted in a wedge action that gave rise to a strong increase in occlusal forces, which were about twice as high as actual tooth load, with wide variation. CONCLUSION: This method of bite force measurement eliminated the influence of occlusal morphology by individual correction for each pair of opposing teeth. To measure the absolute load of antagonistic teeth with thin film transducer foils, one must take into account individual occlusal morphology. Forces measured with the films are a function of both actual tooth load and occlusal morphology.