Detalhe da pesquisa
1.
Structure-activity relationships of 2-pyrimidinecarbohydrazides as utrophin modulators for the potential treatment of Duchenne muscular dystrophy.
Bioorg Med Chem
; 69: 116812, 2022 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35772287
2.
Synthesis of SMT022357 enantiomers and in vivo evaluation in a Duchenne muscular dystrophy mouse model.
Tetrahedron
; 76(2): 130819, 2020 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32713969
3.
Oxidative carbon-carbon bond cleavage is a key step in spiroacetal biosynthesis in the fruit fly Bactrocera cacuminata.
J Org Chem
; 79(17): 7799-821, 2014 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24914610
4.
Decreasing HepG2 Cytotoxicity by Lowering the Lipophilicity of Benzo[d]oxazolephosphinate Ester Utrophin Modulators.
ACS Med Chem Lett
; 11(12): 2421-2427, 2020 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33335663
5.
Potent Thiophene Antagonists of Human Complement C3a Receptor with Anti-Inflammatory Activity.
J Med Chem
; 63(2): 529-541, 2020 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31910011
6.
2-Arylbenzo[d]oxazole Phosphinate Esters as Second-Generation Modulators of Utrophin for the Treatment of Duchenne Muscular Dystrophy.
J Med Chem
; 63(14): 7880-7891, 2020 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32551645
7.
Isolation, Structural Identification, Synthesis, and Pharmacological Profiling of 1,2-trans-Dihydro-1,2-diol Metabolites of the Utrophin Modulator Ezutromid.
J Med Chem
; 63(5): 2547-2556, 2020 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31599580
8.
Exploiting a novel conformational switch to control innate immunity mediated by complement protein C3a.
Nat Commun
; 8(1): 351, 2017 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28839129