Detalhe da pesquisa
1.
Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties.
Proc Natl Acad Sci U S A
; 119(12): e2111405119, 2022 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35294277
2.
Demonstration of brain region-specific neuronal vulnerability in human iPSC-based model of familial Parkinson's disease.
Hum Mol Genet
; 29(7): 1180-1191, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32160287
3.
Urokinase plasminogen activator mediates changes in human astrocytes modeling fragile X syndrome.
Glia
; 69(12): 2947-2962, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34427356
4.
Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition.
Proc Natl Acad Sci U S A
; 115(37): E8765-E8774, 2018 09 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30150378
5.
NF-E2-related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin-1 mutated Alzheimer's disease astrocytes.
Glia
; 68(3): 589-599, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31670864
6.
Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes.
J Neurosci
; 37(49): 11835-11853, 2017 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29089438
7.
Amplifying mitochondrial function rescues adult neurogenesis in a mouse model of Alzheimer's disease.
Neurobiol Dis
; 102: 113-124, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28286181
8.
Genetic manipulation of adult-born hippocampal neurons rescues memory in a mouse model of Alzheimer's disease.
Brain
; 138(Pt 2): 440-55, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25518958
9.
Accelerated high-yield generation of limb-innervating motor neurons from human stem cells.
J Neurosci
; 33(2): 574-86, 2013 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23303937
10.
Direct evidence of Parkinson pathology spread from the gastrointestinal tract to the brain in rats.
Acta Neuropathol
; 128(6): 805-20, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25296989
11.
Inhibition of the serine protease HtrA1 by SerpinE2 suggests an extracellular proteolytic pathway in the control of neural crest migration.
Elife
; 122024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38634469
12.
Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer's disease pathogenesis.
Acta Neuropathol Commun
; 11(1): 150, 2023 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37715247
13.
Cellular Aging Secretes: a Comparison of Bone-Marrow-Derived and Induced Mesenchymal Stem Cells and Their Secretome Over Long-Term Culture.
Stem Cell Rev Rep
; 19(1): 248-263, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36152233
14.
Human iPSC-derived microglia carrying the LRRK2-G2019S mutation show a Parkinson's disease related transcriptional profile and function.
Sci Rep
; 13(1): 22118, 2023 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38092815
15.
Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes.
Front Cell Neurosci
; 16: 878154, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35518645
16.
GABAergic differentiation induced by Mash1 is compromised by the bHLH proteins Neurogenin2, NeuroD1, and NeuroD2.
Cereb Cortex
; 20(5): 1234-44, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19767311
17.
The intracellular milieu of Parkinson's disease patient brain cells modulates alpha-synuclein protein aggregation.
Acta Neuropathol Commun
; 9(1): 153, 2021 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34530929
18.
Generation of the Human Pluripotent Stem-Cell-Derived Astrocyte Model with Forebrain Identity.
Brain Sci
; 11(2)2021 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33572154
19.
TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration.
Cell Rep
; 34(12): 108895, 2021 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33761362
20.
Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas.
Mol Ther
; 17(1): 183-90, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-18985030