Detalhe da pesquisa
1.
A synthetic agent ameliorates polycystic kidney disease by promoting apoptosis of cystic cells through increased oxidative stress.
Proc Natl Acad Sci U S A
; 121(4): e2317344121, 2024 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38241440
2.
Visible Light-Induced One-Pot Carbonylation of Alkyl Halides with Aryl Formates.
J Org Chem
; 89(6): 4205-4209, 2024 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38447064
3.
Dihydro-10H-indeno[1,2-b]benzofurans and Tetrahydroindeno[1,2-c]isochromenes via Stereoselective Intramolecular Carbocation Cascade Cyclization.
J Org Chem
; 89(5): 2964-2983, 2024 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38345392
4.
Metal- and photocatalyst-free approach to visible-light-induced acylation of quinoxalinones.
Org Biomol Chem
; 2024 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38698760
5.
Protein Modification via Nitrile Oxide-Dehydroalanine Cycloaddition: Formation of Isoxazoline Ring on the Protein Backbone.
Chembiochem
; 24(20): e202300268, 2023 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37199473
6.
Synthesis of Naphtho[2,3-d]oxazoles via Ag(I) Acid-Mediated Oxazole-Benzannulation of ortho-Alkynylamidoarylketones.
J Org Chem
; 88(5): 2677-2691, 2023 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35786915
7.
A Mechanistically Deceiving Formation of Aryl(1-indanyl)ketones via Acid-Catalyzed Cyclization of ortho-Alkynylarylmethanols.
J Org Chem
; 88(7): 4172-4186, 2023 Apr 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36941741
8.
Mn(OAc)3-Mediated One-Pot Condensation-Oxidative Annulation of 2-Alkynylanilines and 1,3-Ketoesters: Synthesis of 2-Substituted Quinolines.
J Org Chem
; 88(11): 6736-6749, 2023 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37143349
9.
Base-Mediated and Silver-Catalyzed Divergent Synthesis of Hydroxynaphthalenamides and Phosphorylated Dihydronaphthylamides from Enone-Oxazolones.
J Org Chem
; 88(23): 16520-16538, 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37974421
10.
Divergent synthesis of 3,4-dihydro-2H-benzo[h]chromen-2-one and fluorenone derivatives from ortho-alkynylarylketones.
Org Biomol Chem
; 21(44): 8888-8901, 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37902976
11.
Selective electrophilic cyclization of ortho-carbonylarylacetylenols for the synthesis of cyclopenta[a]naphthalenol and 2-phenylnaphthalen-1-ol analogs.
Org Biomol Chem
; 21(42): 8500-8515, 2023 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37702619
12.
Discovery of N-methylbenzo[d]oxazol-2-amine as new anthelmintic agent through scalable protocol for the synthesis of N-alkylbenzo[d]oxazol-2-amine and N-alkylbenzo[d]thiazol-2-amine derivatives.
Bioorg Chem
; 131: 106287, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36455482
13.
A structure-based virtual high-throughput screening, molecular docking, molecular dynamics and MM/PBSA study identified novel putative drug-like dual inhibitors of trypanosomal cruzain and rhodesain cysteine proteases.
Mol Divers
; 2023 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36617352
14.
Synergistic Lewis-Brønsted Acid Catalysis in Cascade Cyclization of ortho-Alkynylaryl Cyclopropylketones for the Synthesis of 2,3-Dihydronaphtho[1,2-b]furans.
J Org Chem
; 87(22): 15358-15379, 2022 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-36282245
15.
Functionalized Chromans from ortho-Quinone Methides and Arylallenes.
J Org Chem
; 87(23): 15863-15887, 2022 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36373006
16.
Total Synthesis of Palodesangrens A and C.
J Org Chem
; 87(1): 386-398, 2022 01 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34904441
17.
Discovery of potent antiproliferative agents from selected oxygen heterocycles as EGFR tyrosine kinase inhibitors from the U.S. National Cancer Institute database by in silico screening and bioactivity evaluation.
Bioorg Med Chem Lett
; 58: 128524, 2022 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34995690
18.
Photoinduced C-C bond cleavage for the synthesis of 2,4-disubstituted-1-naphthols from indenone derivatives and sulfoxonium ylide.
Org Biomol Chem
; 20(28): 5520-5524, 2022 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-35735093
19.
The Peptide A-3302-B Isolated from a Marine Bacterium Micromonospora sp. Inhibits HSV-2 Infection by Preventing the Viral Egress from Host Cells.
Int J Mol Sci
; 23(2)2022 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35055133
20.
Highly Regioselective Tandem Reaction of Ene-Yne-Oxazolones Induced by H-Phosphonates: Construction of Phosphinylindane Derivatives.
J Org Chem
; 86(14): 9360-9383, 2021 07 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34213338