Detalhe da pesquisa
1.
Tyrosine phosphorylation of Munc18-1 inhibits synaptic transmission by preventing SNARE assembly.
EMBO J
; 37(2): 300-320, 2018 01 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29150433
2.
Interactions Between SNAP-25 and Synaptotagmin-1 Are Involved in Vesicle Priming, Clamping Spontaneous and Stimulating Evoked Neurotransmission.
J Neurosci
; 36(47): 11865-11880, 2016 11 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-27881774
3.
Extension of Helix 12 in Munc18-1 Induces Vesicle Priming.
J Neurosci
; 36(26): 6881-91, 2016 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27358447
4.
Uncovering the "secret" lives of vacuolar fusion pores in living cells.
EMBO J
; 37(19)2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30237311
5.
A Post-Docking Role of Synaptotagmin 1-C2B Domain Bottom Residues R398/399 in Mouse Chromaffin Cells.
J Neurosci
; 35(42): 14172-82, 2015 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26490858
6.
Complexin arrests a pool of docked vesicles for fast Ca2+-dependent release.
EMBO J
; 31(15): 3270-81, 2012 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22705946
7.
SNARE and regulatory proteins induce local membrane protrusions to prime docked vesicles for fast calcium-triggered fusion.
EMBO Rep
; 15(3): 308-14, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24493260
8.
An extended helical conformation in domain 3a of Munc18-1 provides a template for SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex assembly.
J Biol Chem
; 289(14): 9639-50, 2014 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24532794
9.
SNAP25 disease mutations change the energy landscape for synaptic exocytosis due to aberrant SNARE interactions.
Elife
; 122024 Feb 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38411501
10.
Single residues in the complexin N-terminus exhibit distinct phenotypes in synaptic vesicle fusion.
bioRxiv
; 2024 Jan 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38260673
11.
Reduced Protein Stability of 11 Pathogenic Missense STXBP1/MUNC18-1 Variants and Improved Disease Prediction.
Biol Psychiatry
; 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490366
12.
SNAREpin assembly by Munc18-1 requires previous vesicle docking by synaptotagmin 1.
J Biol Chem
; 287(37): 31041-9, 2012 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22810233
13.
Distinct roles of myosin Va in membrane remodeling and exocytosis of secretory granules.
Traffic
; 11(5): 637-50, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20149155
14.
Resolving the function of distinct Munc18-1/SNARE protein interaction modes in a reconstituted membrane fusion assay.
J Biol Chem
; 286(35): 30582-30590, 2011 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21730064
15.
The carboxy-terminal domain of complexin I stimulates liposome fusion.
Proc Natl Acad Sci U S A
; 106(6): 2001-6, 2009 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-19179400
16.
Intracellular and viral membrane fusion: a uniting mechanism.
Curr Opin Cell Biol
; 16(4): 429-35, 2004 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-15261676
17.
A short perinuclear amphipathic α-helix in Apq12 promotes nuclear pore complex biogenesis.
Open Biol
; 11(11): 210250, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34814743
18.
Arrangements of proteins at reconstituted synaptic vesicle fusion sites depend on membrane separation.
FEBS Lett
; 594(21): 3450-3463, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32860428
19.
Complexin Suppresses Spontaneous Exocytosis by Capturing the Membrane-Proximal Regions of VAMP2 and SNAP25.
Cell Rep
; 32(3): 107926, 2020 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32698012
20.
The Interaction of Munc18-1 Helix 11 and 12 with the Central Region of the VAMP2 SNARE Motif Is Essential for SNARE Templating and Synaptic Transmission.
eNeuro
; 7(6)2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-33055194