Detalhe da pesquisa
1.
A phase 1/2a safety, pharmacokinetics, and efficacy study of the novel nucleoside analog FF-10502-01 for the treatment of advanced solid tumors.
Cancer
; 129(10): 1537-1546, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36882377
2.
Efficacy and safety of adjunctive perampanel in adolescent patients with epilepsy: Post hoc analysis of six randomized studies.
Epilepsy Behav
; 104(Pt A): 106876, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31954998
3.
FF-10502, an Antimetabolite with Novel Activity on Dormant Cells, Is Superior to Gemcitabine for Targeting Pancreatic Cancer Cells.
J Pharmacol Exp Ther
; 366(1): 125-135, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29653962
4.
Long-term efficacy and safety of adjunctive perampanel in patients from the Asia-Pacific region with refractory focal-onset seizures in Study 335 open-label extension.
Epilepsia Open
; 9(2): 501-512, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37867420
5.
Discovery of a new type inhibitor of human glyoxalase I by myricetin-based 4-point pharmacophore.
Bioorg Med Chem Lett
; 21(14): 4337-42, 2011 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21669529
6.
Amyloid precursor protein binding protein Fe65 is cleaved by caspases during DNA damage-induced apoptosis.
Biol Pharm Bull
; 34(2): 290-4, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21415543
7.
Glycogen synthase kinase-3ß2 has lower phosphorylation activity to tau than glycogen synthase kinase-3ß1.
Biol Pharm Bull
; 34(1): 146-9, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21212533
8.
Delphinidin, a dietary anthocyanidin in berry fruits, inhibits human glyoxalase I.
Bioorg Med Chem
; 18(19): 7029-33, 2010 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20801663
9.
Structural insights into the hot spot amino acid residues of mushroom tyrosinase for the bindings of thujaplicins.
Bioorg Med Chem
; 18(22): 8112-8, 2010 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20947360
10.
Structure-activity relationship of human GLO I inhibitory natural flavonoids and their growth inhibitory effects.
Bioorg Med Chem
; 16(7): 3969-75, 2008 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18258440
11.
Long-term tolerability, safety and efficacy of adjunctive perampanel in the open-label, dose-ascending Study 231 and extension Study 233 in Japanese patients with epilepsy.
Seizure
; 62: 26-32, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30267941