Detalhe da pesquisa
1.
Self-administered intranasal etripamil using a symptom-prompted, repeat-dose regimen for atrioventricular-nodal-dependent supraventricular tachycardia (RAPID): a multicentre, randomised trial.
Lancet
; 402(10396): 118-128, 2023 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37331368
2.
Gene- and variant-specific efficacy of serum/glucocorticoid-regulated kinase 1 inhibition in long QT syndrome types 1 and 2.
Europace
; 25(5)2023 05 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-37099628
3.
Rationale for and design of a multicenter, placebo-controlled, phase 3 study to assess efficacy and safety of intranasal etripamil for the conversion of paroxysmal supraventricular tachycardia.
Am Heart J
; 253: 20-29, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35728658
4.
Workshop Report: FDA Workshop on Improving Cardiotoxicity Assessment With Human-Relevant Platforms.
Circ Res
; 125(9): 855-867, 2019 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31600125
5.
Is there a role for pharmacokinetic/pharmacodynamic-guided dosing for novel oral anticoagulants?
Am Heart J
; 199: 59-67, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29754667
6.
Scientific white paper on concentration-QTc modeling.
J Pharmacokinet Pharmacodyn
; 45(3): 383-397, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29209907
7.
Correction to: Scientific white paper on concentration-QTc modeling.
J Pharmacokinet Pharmacodyn
; 45(3): 399, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29330761
8.
Long-term electrocardiographic safety monitoring in clinical drug development: A report from the Cardiac Safety Research Consortium.
Am Heart J
; 187: 156-169, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28454799
9.
Solithromycin, a novel macrolide, does not prolong cardiac repolarization: a randomized, three-way crossover study in healthy subjects.
J Antimicrob Chemother
; 72(2): 515-521, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27798210
10.
Finding the rhythm of sudden cardiac death: new opportunities using induced pluripotent stem cell-derived cardiomyocytes.
Circ Res
; 116(12): 1989-2004, 2015 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26044252
11.
NOAC monitoring, reversal agents, and post-approval safety and effectiveness evaluation: A cardiac safety research consortium think tank.
Am Heart J
; 177: 74-86, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27297852
12.
The Cardiac Safety Research Consortium enters its second decade: An invitation to participate.
Am Heart J
; 177: 96-101, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27297854
13.
Cardiovascular safety for once-weekly dulaglutide in type 2 diabetes: a pre-specified meta-analysis of prospectively adjudicated cardiovascular events.
Cardiovasc Diabetol
; 15: 38, 2016 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26912057
14.
Cardiovascular Safety Outcome Trials: A meeting report from the Cardiac Safety Research Consortium.
Am Heart J
; 169(4): 486-95, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25819855
15.
Centralized adjudication of cardiovascular end points in cardiovascular and noncardiovascular pharmacologic trials: a report from the Cardiac Safety Research Consortium.
Am Heart J
; 169(2): 197-204, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25641528
16.
Considerations for assessing the potential effects of antidiabetes drugs on cardiac ventricular repolarization: A report from the Cardiac Safety Research Consortium.
Am Heart J
; 170(1): 23-35, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26093861
17.
Novel oral anticoagulants and reversal agents: Considerations for clinical development.
Am Heart J
; 169(6): 751-7, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26027611
18.
Rechanneling the cardiac proarrhythmia safety paradigm: a meeting report from the Cardiac Safety Research Consortium.
Am Heart J
; 167(3): 292-300, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24576511
19.
Cardiac Safety Research Consortium: can the thorough QT/QTc study be replaced by early QT assessment in routine clinical pharmacology studies? Scientific update and a research proposal for a path forward.
Am Heart J
; 168(3): 262-72, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-25173536
20.
Assessment of drug-induced increases in blood pressure during drug development: report from the Cardiac Safety Research Consortium.
Am Heart J
; 165(4): 477-88, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23537963