1.
Chem Pharm Bull (Tokyo)
; 67(5): 452-460, 2019.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31061370
RESUMO
The Michael reaction of malonates with maleates afforded the corresponding adducts in high yields with high enantioselectivities (up to 98% enantiomeric excess (ee)) by using dilithium 3,3'-dichlorobinaphtholate as a catalyst. The obtained Michael adducts could be converted to optically active tricarboxylic acid (TCA) derivatives via the Krapcho reaction.