A Prospective Cohort Study to Evaluate the Impact of Diet, Exercise, and Lifestyle on Fertility: Design and Baseline Characteristics.

Diet, lifestyle, and psychosocial factors might influence fertility for men and women, although evidence is mixed, and couple-based approaches are needed for assessing associations with reproductive outcomes. The Impact of Diet, Exercise, and Lifestyle (IDEAL) on Fertility Study is a prospective cohort with contemporaneous detailed follow-up of female partners of men enrolled in the Folic Acid and Zinc Supplementation Trial studying couples seeking infertility treatment (2016-2019). Follow-up of men continued for 6 months, while female partners were followed for 9 months while attempting pregnancy and throughout any resulting pregnancy (up to 18 months). Longitudinal data on diet, physical activity (including measurement via wearable device), sleep, and stress were captured at multiple study visits during this follow-up. A subset of women (IDEALplus) also completed daily journals and a body fat assessment via dual-energy x-ray absorptiometry. IDEAL enrolled 920 women, and IDEALPlus enrolled 218. We demonstrated the ability to enroll women in a prospective cohort study contemporaneous to a partner-enrolled randomized trial. In combination with data collected on male partners, IDEAL data facilitates a couple-based approach to understanding associations between lifestyle factors and infertility treatment outcomes. We describe in detail the study design, recruitment, data collection, lessons learned, and baseline characteristics.

Development and pilot outcome data of a midlife women's health assessment clinic: a comprehensive and multidisciplinary approach to health care.

INTRODUCTION: As women enter midlife, health issues and chronic health problems can emerge. The University of Utah Health Science Center's Midlife Women's Health Assessment Clinic was developed to provide a personalized approach to healthy aging by individual assessment, group education, motivational interviewing, and wellness coaching to women. This article describes the model of care and an initial evaluation of this model. METHODS: Four pilot clinics were conducted to determine if the model would be successful. Data analyzed included patient history questionnaires, laboratory and diagnostic test results, new diagnoses, and follow-up recommendations; telephone surveys of patients 2 to 4 weeks after clinic visits; and verbal queries of clinicians about their experiences and recommendations for improving the clinics. RESULTS: Among the 62 women attending the clinics, the most frequent concern was healthy aging. Two-thirds of the women had new diagnoses during the clinics. Both the women and clinicians participating positively evaluated the pilot clinics. DISCUSSION: This model of care could be replicated to provide comprehensive and efficient health care to aging women in a variety of settings.