Detalhe da pesquisa
1.
TRF2 and apollo cooperate with topoisomerase 2alpha to protect human telomeres from replicative damage.
Cell
; 142(2): 230-42, 2010 Jul 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20655466
2.
Telomere Targeting Approaches in Cancer: Beyond Length Maintenance.
Int J Mol Sci
; 23(7)2022 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35409143
3.
TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment.
Nucleic Acids Res
; 47(7): 3365-3382, 2019 04 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30698737
4.
Targeting of Telomeric Repeat-Containing RNA G-Quadruplexes: From Screening to Biophysical and Biological Characterization of a New Hit Compound.
Int J Mol Sci
; 22(19)2021 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34638655
5.
Dyads of G-Quadruplex Ligands Triggering DNA Damage Response and Tumour Cell Growth Inhibition at Subnanomolar Concentration.
Chemistry
; 25(47): 11085-11097, 2019 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31219221
6.
SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage.
Nucleic Acids Res
; 45(4): 1820-1834, 2017 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27923994
7.
Intragenic G-quadruplex structure formed in the human CD133 and its biological and translational relevance.
Nucleic Acids Res
; 44(4): 1579-90, 2016 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26511095
8.
A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.
Nucleic Acids Res
; 43(3): 1759-69, 2015 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25618850
9.
A bimodal fluorescent and photocytotoxic naphthalene diimide for theranostic applications.
Org Biomol Chem
; 14(30): 7238-49, 2016 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27383473
10.
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.
Nucleic Acids Res
; 42(5): 2945-57, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24335081
11.
Shading the TRF2 recruiting function: a new horizon in drug development.
J Am Chem Soc
; 136(48): 16708-11, 2014 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25393214
12.
The ß-arrestin1/endothelin axis bolsters ovarian fibroblast-dependent invadosome activity and cancer cell metastatic potential.
Cell Death Dis
; 15(5): 358, 2024 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38777849
13.
Methods of studying telomere damage induced by quadruplex-ligand complexes.
Methods
; 57(1): 93-9, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22410593
14.
Drug repositioning strategy for the identification of novel telomere-damaging agents: A role for NAMPT inhibitors.
Aging Cell
; 22(11): e13944, 2023 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37858982
15.
Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis.
Proc Natl Acad Sci U S A
; 106(8): 2806-11, 2009 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-19202075
16.
Fibroblast-Induced Paradoxical PI3K Pathway Activation in PTEN-Competent Colorectal Cancer: Implications for Therapeutic PI3K/mTOR Inhibition.
Front Oncol
; 12: 862806, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35719951
17.
Ligand-based drug repurposing strategy identified SARS-CoV-2 RNA G-quadruplex binders.
Chem Commun (Camb)
; 58(85): 11913-11916, 2022 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-36196950
18.
Stabilization of quadruplex DNA perturbs telomere replication leading to the activation of an ATR-dependent ATM signaling pathway.
Nucleic Acids Res
; 37(16): 5353-64, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19596811
19.
Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect.
J Clin Invest
; 117(11): 3236-47, 2007 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-17932567
20.
G-quadruplex Stabilization Fuels the ALT Pathway in ALT-positive Osteosarcoma Cells.
Genes (Basel)
; 11(3)2020 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32183119