Detalhe da pesquisa
1.
Sex-Specific Regulation of ß-Secretase: A Novel Estrogen Response Element (ERE)-Dependent Mechanism in Alzheimer's Disease.
J Neurosci
; 42(6): 1154-1165, 2022 02 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34903570
2.
Tryptophan in Nutrition and Health 2.0.
Int J Mol Sci
; 24(8)2023 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37108272
3.
Nitric Oxide as a Determinant of Human Longevity and Health Span.
Int J Mol Sci
; 24(19)2023 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37833980
4.
The role of the adaptive immune system and T cell dysfunction in neurodegenerative diseases.
J Neuroinflammation
; 19(1): 251, 2022 Oct 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36209107
5.
Indoles as essential mediators in the gut-brain axis. Their role in Alzheimer's disease.
Neurobiol Dis
; 156: 105403, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34087380
6.
Resolution of inflammation is altered in Alzheimer's disease.
Alzheimers Dement
; 11(1): 40-50.e1-2, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24530025
7.
Evidence for lymphatic Aß clearance in Alzheimer's transgenic mice.
Neurobiol Dis
; 71: 215-9, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25102344
8.
Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury.
Alzheimers Dement
; 10(1 Suppl): S62-75, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24529527
9.
The seeds of its regulation: natural antisense transcripts as single-gene control switches in neurodegenerative disorders.
Ageing Res Rev
; : 102336, 2024 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38740308
10.
DPP-4 inhibitors sitagliptin and PF-00734,200 mitigate dopaminergic neurodegeneration, neuroinflammation and behavioral impairment in the rat 6-OHDA model of Parkinson's disease.
Geroscience
; 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38563864
11.
The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice.
FASEB J
; 26(7): 2899-910, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22459153
12.
Major carboxyl terminal fragments generated by γ-secretase processing of the Alzheimer amyloid precursor are 50 and 51 amino acids long.
Am J Geriatr Psychiatry
; 21(5): 474-83, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23570890
13.
GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism.
Proc Natl Acad Sci U S A
; 106(4): 1285-90, 2009 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19164583
14.
Current Advances in Adeno-Associated Virus-Mediated Gene Therapy to Prevent Acquired Hearing Loss.
J Assoc Res Otolaryngol
; 23(5): 569-578, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36002664
15.
Mechanistic Insights Into Gut Microbiome Dysbiosis-Mediated Neuroimmune Dysregulation and Protein Misfolding and Clearance in the Pathogenesis of Chronic Neurodegenerative Disorders.
Front Neurosci
; 16: 836605, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35281490
16.
Targets for AD treatment: conflicting messages from γ-secretase inhibitors.
J Neurochem
; 117(3): 359-74, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21320126
17.
Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.
Neuron
; 51(1): 29-42, 2006 Jul 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-16815330
18.
Pigment epithelium-derived factor maintains retinal pigment epithelium function by inhibiting vascular endothelial growth factor-R2 signaling through gamma-secretase.
J Biol Chem
; 284(44): 30177-86, 2009 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-19723623
19.
Amyloid-ß precursor protein synthesis inhibitors for Alzheimer's disease treatment.
Ann Neurol
; 76(4): 629-30, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25146731
20.
Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer's disease.
Transl Psychiatry
; 10(1): 47, 2020 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32066688