Detalhe da pesquisa
1.
Structural, biochemical, and biophysical characterization of idelalisib binding to phosphoinositide 3-kinase δ.
J Biol Chem
; 290(13): 8439-46, 2015 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25631052
2.
GS-5806 inhibits pre- to postfusion conformational changes of the respiratory syncytial virus fusion protein.
Antimicrob Agents Chemother
; 59(11): 7109-12, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26324264
3.
New class of HIV-1 integrase (IN) inhibitors with a dual mode of action.
J Biol Chem
; 287(25): 21189-203, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22535962
4.
A trimer of dimers is the basic building block for human immunodeficiency virus-1 capsid assembly.
Biochemistry
; 51(22): 4416-28, 2012 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22564075
5.
Dithiothreitol causes HIV-1 integrase dimer dissociation while agents interacting with the integrase dimer interface promote dimer formation.
Biochemistry
; 50(10): 1567-81, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21222490
6.
Dimer dissociation and unfolding mechanism of coagulation factor XI apple 4 domain: spectroscopic and mutational analysis.
J Mol Biol
; 367(2): 558-73, 2007 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-17257616
7.
Structural Basis for Activity and Specificity of an Anticoagulant Anti-FXIa Monoclonal Antibody and a Reversal Agent.
Structure
; 26(2): 187-198.e4, 2018 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29336885
8.
Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study.
J Med Chem
; 58(4): 1630-43, 2015 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25574686
9.
Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex.
J Mol Biol
; 397(4): 967-78, 2010 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-20156454
10.
Solution structure of the A4 domain of factor XI sheds light on the mechanism of zymogen activation.
Proc Natl Acad Sci U S A
; 104(40): 15693-8, 2007 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-17884987
11.
Characterization and structural analyses of nonspecific lipid transfer protein 1 from mung bean.
Biochemistry
; 44(15): 5703-12, 2005 Apr 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-15823028
12.
Purification and characterization of a novel 7-kDa non-specific lipid transfer protein-2 from rice (Oryza sativa).
Biochem Biophys Res Commun
; 294(3): 535-40, 2002 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-12056799
13.
Solution structure of plant nonspecific lipid transfer protein-2 from rice (Oryza sativa).
J Biol Chem
; 277(38): 35267-73, 2002 Sep 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-12011089
14.
Binding mechanism of nonspecific lipid transfer proteins and their role in plant defense.
Biochemistry
; 43(43): 13628-36, 2004 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-15504025
15.
Mutagenesis study on the zebra fish SOX9 high-mobility group: comparison of sequence and non-sequence specific HMG domains.
Biochemistry
; 42(38): 11183-93, 2003 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-14503868