Detalhe da pesquisa
1.
Tinostamustine (EDO-S101), an Alkylating Deacetylase Inhibitor, Enhances the Efficacy of Daratumumab in Multiple Myeloma by Upregulation of CD38 and NKG2D Ligands.
Int J Mol Sci
; 25(9)2024 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38731936
2.
Chloroquine-Induced DNA Damage Synergizes with Nonhomologous End Joining Inhibition to Cause Ovarian Cancer Cell Cytotoxicity.
Int J Mol Sci
; 23(14)2022 Jul 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35886866
3.
Synergistic DNA-damaging effect in multiple myeloma with the combination of zalypsis, bortezomib and dexamethasone.
Haematologica
; 102(1): 168-175, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27540138
4.
The kinesin spindle protein inhibitor filanesib enhances the activity of pomalidomide and dexamethasone in multiple myeloma.
Haematologica
; 102(12): 2113-2124, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28860344
5.
Effect of mTORC1/mTORC2 inhibition on T cell function: potential role in graft-versus-host disease control.
Br J Haematol
; 173(5): 754-68, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26914848
6.
Alterations in gene expression levels provide early indicators of chemical stress during Xenopus laevis embryo development: A case study with perfluorooctane sulfonate (PFOS).
Ecotoxicol Environ Saf
; 127: 51-60, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26802562
7.
Detailed characterization of multiple myeloma circulating tumor cells shows unique phenotypic, cytogenetic, functional, and circadian distribution profile.
Blood
; 122(22): 3591-8, 2013 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-24072855
8.
Preclinical evaluation of the simultaneous inhibition of MCL-1 and BCL-2 with the combination of S63845 and venetoclax in multiple myeloma.
Haematologica
; 105(3): e116-e120, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31320555
9.
EGFR amplification and EGFRvIII predict and participate in TAT-Cx43266-283 antitumor response in preclinical glioblastoma models.
Neuro Oncol
; 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38507464
10.
CD20 positive cells are undetectable in the majority of multiple myeloma cell lines and are not associated with a cancer stem cell phenotype.
Haematologica
; 97(7): 1110-4, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22315496
11.
Transcriptomic rationale for the synergy observed with dasatinib + bortezomib + dexamethasone in multiple myeloma.
Ann Hematol
; 91(2): 257-69, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21720745
12.
Zalypsis: a novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to DNA double-strand breaks.
Blood
; 113(16): 3781-91, 2009 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19020308
13.
Zalypsis has in vitro activity in acute myeloid blasts and leukemic progenitor cells through the induction of a DNA damage response.
Haematologica
; 96(5): 687-95, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21330323
14.
Stroma-Mediated Resistance to S63845 and Venetoclax through MCL-1 and BCL-2 Expression Changes Induced by miR-193b-3p and miR-21-5p Dysregulation in Multiple Myeloma.
Cells
; 10(3)2021 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33806619
15.
Targeting aberrant DNA methylation in mesenchymal stromal cells as a treatment for myeloma bone disease.
Nat Commun
; 12(1): 421, 2021 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33462210
16.
In vitro and in vivo rationale for the triple combination of panobinostat (LBH589) and dexamethasone with either bortezomib or lenalidomide in multiple myeloma.
Haematologica
; 95(5): 794-803, 2010 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19951978
17.
Protein Translation Inhibition is Involved in the Activity of the Pan-PIM Kinase Inhibitor PIM447 in Combination with Pomalidomide-Dexamethasone in Multiple Myeloma.
Cancers (Basel)
; 12(10)2020 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32987735
18.
CRISPR/Cas9-generated models uncover therapeutic vulnerabilities of del(11q) CLL cells to dual BCR and PARP inhibition.
Leukemia
; 34(6): 1599-1612, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31974435
19.
C3G promotes a selective release of angiogenic factors from activated mouse platelets to regulate angiogenesis and tumor metastasis.
Oncotarget
; 8(67): 110994-111011, 2017 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-29340032
20.
Amiloride, An Old Diuretic Drug, Is a Potential Therapeutic Agent for Multiple Myeloma.
Clin Cancer Res
; 23(21): 6602-6615, 2017 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28790111