Detalhe da pesquisa
1.
Bacterial fitness landscapes stratify based on proteome allocation associated with discrete aero-types.
PLoS Comput Biol
; 17(1): e1008596, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33465077
2.
The Bitome: digitized genomic features reveal fundamental genome organization.
Nucleic Acids Res
; 48(18): 10157-10163, 2020 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32976587
3.
Cellular responses to reactive oxygen species are predicted from molecular mechanisms.
Proc Natl Acad Sci U S A
; 116(28): 14368-14373, 2019 07 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31270234
4.
OxyR Is a Convergent Target for Mutations Acquired during Adaptation to Oxidative Stress-Prone Metabolic States.
Mol Biol Evol
; 37(3): 660-667, 2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31651953
5.
Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity.
BMC Genomics
; 21(1): 514, 2020 Jul 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32711472
6.
Enzyme promiscuity shapes adaptation to novel growth substrates.
Mol Syst Biol
; 15(4): e8462, 2019 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30962359
7.
Laboratory evolution reveals a two-dimensional rate-yield tradeoff in microbial metabolism.
PLoS Comput Biol
; 15(6): e1007066, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31158228
8.
The genetic basis for adaptation of model-designed syntrophic co-cultures.
PLoS Comput Biol
; 15(3): e1006213, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30822347
9.
The emergence of adaptive laboratory evolution as an efficient tool for biological discovery and industrial biotechnology.
Metab Eng
; 56: 1-16, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31401242
10.
Adaptive laboratory evolution resolves energy depletion to maintain high aromatic metabolite phenotypes in Escherichia coli strains lacking the Phosphotransferase System.
Metab Eng
; 48: 233-242, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29906504
11.
Adaptation to the coupling of glycolysis to toxic methylglyoxal production in tpiA deletion strains of Escherichia coli requires synchronized and counterintuitive genetic changes.
Metab Eng
; 48: 82-93, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29842925
12.
Multiple Optimal Phenotypes Overcome Redox and Glycolytic Intermediate Metabolite Imbalances in Escherichia coli pgi Knockout Evolutions.
Appl Environ Microbiol
; 84(19)2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30054360
13.
Laboratory Evolution to Alternating Substrate Environments Yields Distinct Phenotypic and Genetic Adaptive Strategies.
Appl Environ Microbiol
; 83(13)2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28455337
14.
Evolution of Escherichia coli to 42 °C and subsequent genetic engineering reveals adaptive mechanisms and novel mutations.
Mol Biol Evol
; 31(10): 2647-62, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25015645
15.
Use of adaptive laboratory evolution to discover key mutations enabling rapid growth of Escherichia coli K-12 MG1655 on glucose minimal medium.
Appl Environ Microbiol
; 81(1): 17-30, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25304508
16.
Adaptive evolution of a minimal organism with a synthetic genome.
iScience
; 26(9): 107500, 2023 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37636038
17.
Synthetic cross-phyla gene replacement and evolutionary assimilation of major enzymes.
Nat Ecol Evol
; 4(10): 1402-1409, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32778753
18.
Pseudogene repair driven by selection pressure applied in experimental evolution.
Nat Microbiol
; 4(3): 386-389, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30692668
19.
Evolution of gene knockout strains of E. coli reveal regulatory architectures governed by metabolism.
Nat Commun
; 9(1): 3796, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30228271
20.
Growth Adaptation of gnd and sdhCB Escherichia coli Deletion Strains Diverges From a Similar Initial Perturbation of the Transcriptome.
Front Microbiol
; 9: 1793, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-30131786