Detalhe da pesquisa
1.
Chitin-mediated blockade of chitinase-like proteins reduces tumor immunosuppression, inhibits lymphatic metastasis and enhances anti-PD-1 efficacy in complementary TNBC models.
Breast Cancer Res
; 26(1): 63, 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38605414
2.
Lipid Nanoparticle Encapsulation Empowers Poly(I:C) to Activate Cytoplasmic RLRs and Thereby Increases Its Adjuvanticity.
Small
; 20(10): e2306892, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-37867244
3.
A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity.
Mol Ther
; 30(9): 2968-2983, 2022 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35450821
4.
In Vivo Validation of a Reversible Small Molecule-Based Switch for Synthetic Self-Amplifying mRNA Regulation.
Mol Ther
; 29(3): 1164-1173, 2021 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33186690
5.
Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs.
Mol Ther
; 29(4): 1370-1381, 2021 04 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33484964
6.
Squaric Ester-Based, pH-Degradable Nanogels: Modular Nanocarriers for Safe, Systemic Administration of Toll-like Receptor 7/8 Agonistic Immune Modulators.
J Am Chem Soc
; 143(26): 9872-9883, 2021 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34166595
7.
Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine*.
Angew Chem Int Ed Engl
; 60(17): 9467-9473, 2021 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33464672
8.
Potent and Prolonged Innate Immune Activation by Enzyme-Responsive Imidazoquinoline TLR7/8 Agonist Prodrug Vesicles.
J Am Chem Soc
; 142(28): 12133-12139, 2020 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32524819
9.
Small-molecule-based regulation of RNA-delivered circuits in mammalian cells.
Nat Chem Biol
; 14(11): 1043-1050, 2018 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30327560
10.
Potent Lymphatic Translocation and Spatial Control Over Innate Immune Activation by Polymer-Lipid Amphiphile Conjugates of Small-Molecule TLR7/8 Agonists.
Angew Chem Int Ed Engl
; 58(43): 15390-15395, 2019 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31397948
11.
Lymph-Node-Targeted Immune Activation by Engineered Block Copolymer Amphiphiles-TLR7/8 Agonist Conjugates.
J Am Chem Soc
; 140(43): 14300-14307, 2018 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-30277761
12.
Comparison of the Expression Kinetics and Immunostimulatory Activity of Replicating mRNA, Nonreplicating mRNA, and pDNA after Intradermal Electroporation in Pigs.
Mol Pharm
; 15(2): 377-384, 2018 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29297692
13.
Evaluation of a xenogeneic vascular endothelial growth factor-2 vaccine in two preclinical metastatic tumor models in mice.
Cancer Immunol Immunother
; 66(12): 1545-1555, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28776079
14.
Low-dose single-shot COVID-19 mRNA vaccines lie ahead.
Mol Ther
; 29(6): 1944-1945, 2021 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34015254
15.
Corticosteroids and mRNA Vaccines: A Word of Caution.
Mol Ther
; 29(3): 893-894, 2021 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33549165
16.
Coadministration of a Plasmid Encoding HIV-1 Gag Enhances the Efficacy of Cancer DNA Vaccines.
Mol Ther
; 24(9): 1686-96, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27434590
17.
Comparison of the Adipose and Luminal Mammary Gland Compartment as Orthotopic Inoculation Sites in a 4T1-Based Immunocompetent Preclinical Model for Triple-Negative Breast Cancer.
J Mammary Gland Biol Neoplasia
; 21(3-4): 113-122, 2016 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27714576
18.
Corrigendum: Sterilizing Immunity against SARS-CoV-2 Infection in Mice by a Single-Shot and Lipid Amphiphile Imidazoquinoline TLR7/8 Agonist-Adjuvanted Recombinant Spike Protein Vaccine.
Angew Chem Int Ed Engl
; 60(31): 16741-16742, 2021 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34278670
19.
Efficient in vitro and in vivo transfection of self-amplifying mRNA with linear poly(propylenimine) and poly(ethylenimine-propylenimine) random copolymers as non-viral carriers.
J Mater Chem B
; 12(16): 3927-3946, 2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38563779
20.
A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis.
Breast Cancer Res
; 15(6): R116, 2013 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24330716