Detalhe da pesquisa
1.
Human PLD structures enable drug design and characterization of isoenzyme selectivity.
Nat Chem Biol
; 16(4): 391-399, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32042197
2.
Optimization of a novel piperazinone series as potent selective peripheral covalent BTK inhibitors.
Bioorg Med Chem Lett
; 60: 128549, 2022 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35041943
3.
Novel VMAT planning technique improves dosimetry for head and neck cancer patients undergoing definitive chemoradiotherapy.
Acta Oncol
; 62(2): 189-193, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36790072
4.
Corrigendum to "Optimization of a novel piperazinone series as potent selective peripheral covalent BTK inhibitors" [Bioorg. Med. Chem. Lett. 60 (2022) 128549].
Bioorg Med Chem Lett
; 72: 128856, 2022 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35728998
5.
Rapid Resolution of Polyhydramnios Foretells Circulatory Collapse for the Donor Twin in Feto-Fetal Transfusion Syndrome.
P R Health Sci J
; 35(1): 43-5, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26932285
6.
Discovery and Preclinical Characterization of BIIB129, a Covalent, Selective, and Brain-Penetrant BTK Inhibitor for the Treatment of Multiple Sclerosis.
J Med Chem
; 67(10): 8122-8140, 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38712838
7.
Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis.
J Med Chem
; 65(2): 1206-1224, 2022 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34734694
8.
A proprotein convertase subtilisin-like/kexin type 9 (PCSK9) C-terminal domain antibody antigen-binding fragment inhibits PCSK9 internalization and restores low density lipoprotein uptake.
J Biol Chem
; 285(17): 12882-91, 2010 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-20172854
9.
Discovery of Potent, Selective, and Brain-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors that Modulate Brain Inflammation In Vivo.
J Med Chem
; 64(20): 15402-15419, 2021 10 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34653340
10.
Next-generation Bruton's tyrosine kinase inhibitor BIIB091 selectively and potently inhibits B cell and Fc receptor signaling and downstream functions in B cells and myeloid cells.
Clin Transl Immunology
; 10(6): e1295, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34141433
11.
Evaluation of respiration-correlated digital tomosynthesis in lung.
Med Phys
; 37(3): 1237-45, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20384261
12.
Use of corticocancellous allogeneic bone blocks for augmentation of alveolar bone defects.
Int J Oral Maxillofac Implants
; 25(1): 153-62, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20209198
13.
Discovery of CNS-Penetrant Apoptosis Signal-Regulating Kinase 1 (ASK1) Inhibitors.
ACS Med Chem Lett
; 11(4): 485-490, 2020 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32292554
14.
From phase-based to displacement-based gating: a software tool to facilitate respiration-gated radiation treatment.
J Appl Clin Med Phys
; 10(4): 132-141, 2009 Oct 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19918227
15.
Rational Design and Optimization of a Novel Class of Macrocyclic Apoptosis Signal-Regulating Kinase 1 Inhibitors.
J Med Chem
; 62(23): 10740-10756, 2019 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31710475
16.
Discovery of betamethasone 17alpha-carbamates as dissociated glucocorticoid receptor modulators in the rat.
Bioorg Med Chem
; 16(16): 7535-42, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18691892
17.
Novel N-arylpyrazolo[3,2-c]-based ligands for the glucocorticoid receptor: receptor binding and in vivo activity.
J Med Chem
; 47(10): 2441-52, 2004 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-15115388
18.
Skeletal muscle: a dual system to measure glucocorticoid-dependent transactivation and transrepression of gene regulation.
J Steroid Biochem Mol Biol
; 88(2): 191-201, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15084351
19.
Quantitative determination of human interleukin 22 (IL-22) in serum using Singulex-Erenna® technology.
J Immunol Methods
; 390(1-2): 30-4, 2013 Apr 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23313291
20.
The importance of family management, closeness with father and family structure in early adolescent alcohol use.
Addiction
; 105(10): 1750-8, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20670349