Detalhe da pesquisa
1.
SEPT8 modulates ß-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1.
J Cell Sci
; 129(11): 2224-38, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27084579
2.
Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models.
Neurobiol Dis
; 85: 187-205, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26563932
3.
Bepridil decreases Aß and calcium levels in the thalamus after middle cerebral artery occlusion in rats.
J Cell Mol Med
; 16(11): 2754-67, 2012 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22805236
4.
Down-regulation of seladin-1 increases BACE1 levels and activity through enhanced GGA3 depletion during apoptosis.
J Biol Chem
; 284(49): 34433-43, 2009 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19815556
5.
Effects of Alzheimer's Disease-Associated Risk Loci on Amyloid-ß Accumulation in the Brain of Idiopathic Normal Pressure Hydrocephalus Patients.
J Alzheimers Dis
; 55(3): 995-1003, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-27802227
6.
PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease.
Stem Cell Reports
; 9(6): 1885-1897, 2017 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29153989
7.
Hypoxia and GABA shunt activation in the pathogenesis of Alzheimer's disease.
Neurochem Int
; 92: 13-24, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26617286
8.
Genetic Variation in δ-Opioid Receptor Associates with Increased ß- and γ-Secretase Activity in the Late Stages of Alzheimer's Disease.
J Alzheimers Dis
; 48(2): 507-16, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26402014
9.
Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models.
Neurobiol Aging
; 36(2): 1221.e15-28, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25281018
10.
Effects of Alzheimer's disease-associated risk loci on cerebrospinal fluid biomarkers and disease progression: a polygenic risk score approach.
J Alzheimers Dis
; 43(2): 565-73, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25096612
11.
Increased γ-secretase activity in idiopathic normal pressure hydrocephalus patients with ß-amyloid pathology.
PLoS One
; 9(4): e93717, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24699723
12.
Effects of NR1H3 genetic variation on the expression of liver X receptor α and the progression of Alzheimer's disease.
PLoS One
; 8(11): e80700, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24278306
13.
Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's disease.
J Alzheimers Dis
; 37(1): 217-32, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23970038
14.
Genetic analysis of genes involved in amyloid-ß degradation and clearance in Alzheimer's disease.
J Alzheimers Dis
; 28(3): 553-9, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22027013
15.
Effects of memantine and donepezil on cortical and hippocampal acetylcholine levels and object recognition memory in rats.
Neuropharmacology
; 61(5-6): 891-9, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21704049
16.
Cysteine 27 variant of the delta-opioid receptor affects amyloid precursor protein processing through altered endocytic trafficking.
Mol Cell Biol
; 31(11): 2326-40, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21464208
17.
An association study of 21 potential Alzheimer's disease risk genes in a Finnish population.
J Alzheimers Dis
; 21(3): 763-7, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20693638
18.
A novel delayed non-match to sample object recognition task that allows simultaneous in vivo microdialysis.
J Neurosci Methods
; 189(2): 210-5, 2010 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20394774
19.
CALHM1 P86L polymorphism does not alter amyloid-beta or tau in cerebrospinal fluid.
Neurosci Lett
; 469(2): 265-7, 2010 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-20005921
20.
Quantitative determination of acetylcholine in microdialysis samples using liquid chromatography/atmospheric pressure spray ionization mass spectrometry.
Rapid Commun Mass Spectrom
; 21(18): 2933-43, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17680629