Detalhe da pesquisa
1.
DNA damage remodels the MITF interactome to increase melanoma genomic instability.
Genes Dev
; 38(1-2): 70-94, 2024 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38316520
2.
BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma.
Genes Dev
; 33(5-6): 310-332, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30804224
3.
The glutamate/aspartate transporter EAAT1 is crucial for T-cell acute lymphoblastic leukemia proliferation and survival.
Haematologica
; 2024 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38813748
4.
Homologous recombination repair intermediates promote efficient de novo telomere addition at DNA double-strand breaks.
Nucleic Acids Res
; 48(3): 1271-1284, 2020 02 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31828313
5.
Complex inhibitory effects of nitric oxide on autophagy.
Mol Cell
; 43(1): 19-32, 2011 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21726807
6.
A role for human homologous recombination factors in suppressing microhomology-mediated end joining.
Nucleic Acids Res
; 44(12): 5743-57, 2016 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27131361
7.
The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast.
Nucleic Acids Res
; 44(4): 1703-17, 2016 Feb 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26682798
8.
Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics.
Proc Natl Acad Sci U S A
; 112(31): E4281-7, 2015 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26195741
9.
Autophagy, lipophagy and lysosomal lipid storage disorders.
Biochim Biophys Acta
; 1861(4): 269-84, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26778751
10.
Regulation of mammalian autophagy in physiology and pathophysiology.
Physiol Rev
; 90(4): 1383-435, 2010 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-20959619
11.
The DNA damage checkpoint pathway promotes extensive resection and nucleotide synthesis to facilitate homologous recombination repair and genome stability in fission yeast.
Nucleic Acids Res
; 42(9): 5644-56, 2014 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-24623809
12.
N-acetyl-serotonin offers neuroprotection through inhibiting mitochondrial death pathways and autophagic activation in experimental models of ischemic injury.
J Neurosci
; 34(8): 2967-78, 2014 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24553937
13.
Amino acids and autophagy: cross-talk and co-operation to control cellular homeostasis.
Amino Acids
; 47(10): 2065-88, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24965527
14.
Components of a Fanconi-like pathway control Pso2-independent DNA interstrand crosslink repair in yeast.
PLoS Genet
; 8(8): e1002884, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22912599
15.
Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models.
Cell Death Dis
; 15(5): 382, 2024 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-38821960
16.
Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers.
Biochem Soc Trans
; 41(5): 1103-30, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24059496
17.
Chemical screening platforms for autophagy drug discovery to identify therapeutic candidates for Huntington's disease and other neurodegenerative disorders.
Drug Discov Today Technol
; 10(1): e137-44, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-24050242
18.
Deletion of the huntingtin polyglutamine stretch enhances neuronal autophagy and longevity in mice.
PLoS Genet
; 6(2): e1000838, 2010 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-20140187
19.
Metabolic function of autophagy is essential for cell survival.
Autophagy
; 19(8): 2395-2397, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36727253
20.
The autophagy-NAD axis in longevity and disease.
Trends Cell Biol
; 33(9): 788-802, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36878731