Detalhe da pesquisa
1.
A Ca2+-Dependent Mechanism Boosting Glycolysis and OXPHOS by Activating Aralar-Malate-Aspartate Shuttle, upon Neuronal Stimulation.
J Neurosci
; 42(19): 3879-3895, 2022 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35387872
2.
A tribute to Sebastián Cerdán and his key contributions to brain metabolism.
J Neurochem
; 2023 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37169729
3.
Effective therapeutic strategies in a preclinical mouse model of Charcot-Marie-Tooth disease.
Hum Mol Genet
; 30(24): 2441-2455, 2021 11 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-34274972
4.
AGC1 Deficiency: Pathology and Molecular and Cellular Mechanisms of the Disease.
Int J Mol Sci
; 23(1)2022 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35008954
5.
ßOHB Protective Pathways in Aralar-KO Neurons and Brain: An Alternative to Ketogenic Diet.
J Neurosci
; 40(48): 9293-9305, 2020 11 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33087477
6.
Mitochondria and calcium defects correlate with axonal dysfunction in GDAP1-related Charcot-Marie-Tooth mouse model.
Neurobiol Dis
; 152: 105300, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33582224
7.
De Novo Mutations in SLC25A24 Cause a Disorder Characterized by Early Aging, Bone Dysplasia, Characteristic Face, and Early Demise.
Am J Hum Genet
; 101(5): 844-855, 2017 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29100094
8.
Extracellular ATP and glutamate drive pyruvate production and energy demand to regulate mitochondrial respiration in astrocytes.
Glia
; 67(4): 759-774, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30623988
9.
The Response to Stimulation in Neurons and Astrocytes.
Neurochem Res
; 44(10): 2385-2391, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31016552
10.
Calcium Deregulation and Mitochondrial Bioenergetics in GDAP1-Related CMT Disease.
Int J Mol Sci
; 20(2)2019 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30669311
11.
Role of MDH2 pathogenic variant in pheochromocytoma and paraganglioma patients.
Genet Med
; 20(12): 1652-1662, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30008476
12.
L-Lactate-Mediated Neuroprotection against Glutamate-Induced Excitotoxicity Requires ARALAR/AGC1.
J Neurosci
; 36(16): 4443-56, 2016 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27098689
13.
Phototransduction Influences Metabolic Flux and Nucleotide Metabolism in Mouse Retina.
J Biol Chem
; 291(9): 4698-710, 2016 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-26677218
14.
Calcium regulation of mitochondrial carriers.
Biochim Biophys Acta
; 1863(10): 2413-21, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27033520
15.
Glutamate excitotoxicity and Ca2+-regulation of respiration: Role of the Ca2+ activated mitochondrial transporters (CaMCs).
Biochim Biophys Acta
; 1857(8): 1158-1166, 2016 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-27060251
16.
ARALAR/AGC1 deficiency, a neurodevelopmental disorder with severe impairment of neuronal mitochondrial respiration, does not produce a primary increase in brain lactate.
J Neurochem
; 142(1): 132-139, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28429368
17.
Uncoupling Protein 2 (UCP2) Function in the Brain as Revealed by the Cerebral Metabolism of (1-13C)-Glucose.
Neurochem Res
; 42(1): 108-114, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-27401256
18.
Pyruvate kinase and aspartate-glutamate carrier distributions reveal key metabolic links between neurons and glia in retina.
Proc Natl Acad Sci U S A
; 111(43): 15579-84, 2014 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25313047
19.
Mitochondrial ATP-Mg/Pi carrier SCaMC-3/Slc25a23 counteracts PARP-1-dependent fall in mitochondrial ATP caused by excitotoxic insults in neurons.
J Neurosci
; 35(8): 3566-81, 2015 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25716855
20.
Deficient glucose and glutamine metabolism in Aralar/AGC1/Slc25a12 knockout mice contributes to altered visual function.
Mol Vis
; 22: 1198-1212, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27746674