Detalhe da pesquisa
1.
Hypothalamic-pituitary-adrenal (HPA) axis activity and anxiety-like behavior during aging: A test of the glucocorticoid cascade hypothesis in amyloidogenic APPswe/PS1dE9 mice.
Gen Comp Endocrinol
; 330: 114126, 2023 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36122793
2.
PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R).
Proc Natl Acad Sci U S A
; 116(5): 1686-1691, 2019 01 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30635412
3.
Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of α-synucleinopathy.
Acta Neuropathol
; 138(4): 551-574, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31168644
4.
Association between serotonin denervation and resting-state functional connectivity in mild cognitive impairment.
Hum Brain Mapp
; 38(7): 3391-3401, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28379618
5.
Sex-related dimorphism in dentate gyrus atrophy and behavioral phenotypes in an inducible tTa:APPsi transgenic model of Alzheimer's disease.
Neurobiol Dis
; 96: 171-185, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27569580
6.
Acute stressors do not impair short-term memory or attention in an aged mouse model of amyloidosis.
Front Behav Neurosci
; 17: 1151833, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37250187
7.
NMDA Receptor-Arc Signaling Is Required for Memory Updating and Is Disrupted in Alzheimer's Disease.
Biol Psychiatry
; 94(9): 706-720, 2023 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36796600
8.
Longitudinal assessment of cognitive function in the APPswe/PS1dE9 mouse model of Alzheimer's-related beta-amyloidosis.
Neurobiol Aging
; 128: 85-99, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37120419
9.
Synthesis and biodistribution of [11C]A-836339, a new potential radioligand for PET imaging of cannabinoid type 2 receptors (CB2).
Bioorg Med Chem
; 18(14): 5202-7, 2010 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20554448
10.
Increased Sparsity of Hippocampal CA1 Neuronal Ensembles in a Mouse Model of Down Syndrome Assayed by Arc Expression.
Front Neural Circuits
; 11: 6, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28217086
11.
Intranasal post-cardiac arrest treatment with orexin-A facilitates arousal from coma and ameliorates neuroinflammation.
PLoS One
; 12(9): e0182707, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28957432
12.
Environmental enrichment mitigates cognitive deficits in a mouse model of Alzheimer's disease.
J Neurosci
; 25(21): 5217-24, 2005 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-15917461
13.
BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions.
J Neurosci
; 25(50): 11693-709, 2005 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-16354928
14.
Effectiveness of estrogen replacement in restoration of cognitive function after long-term estrogen withdrawal in aging rats.
J Neurosci
; 22(24): 10985-95, 2002 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12486194
15.
Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer disease.
PLoS Med
; 2(12): e355, 2005 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-16279840
16.
Cannabinoid CB2 Receptors in a Mouse Model of Aß Amyloidosis: Immunohistochemical Analysis and Suitability as a PET Biomarker of Neuroinflammation.
PLoS One
; 10(6): e0129618, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26086915
17.
Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice.
Mol Neurodegener
; 8: 18, 2013 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23764200
18.
Alzheimer's therapeutics: translation of preclinical science to clinical drug development.
Neuropsychopharmacology
; 37(1): 261-77, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21937983
19.
Partial depletion of CREB-binding protein reduces life expectancy in a mouse model of Huntington disease.
J Neuropathol Exp Neurol
; 69(4): 396-404, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20448484
20.
Modeling an anti-amyloid combination therapy for Alzheimer's disease.
Sci Transl Med
; 2(13): 13ra1, 2010 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-20371462