Detalhe da pesquisa
1.
Curcumin as an Epigenetic Therapeutic Agent in Myelodysplastic Syndromes (MDS).
Int J Mol Sci
; 23(1)2021 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-35008835
2.
Integrated genome-scale analysis of the transcriptional regulatory landscape in a blood stem/progenitor cell model.
Blood
; 127(13): e12-23, 2016 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-26809507
3.
Gfi1b: a key player in the genesis and maintenance of acute myeloid leukemia and myelodysplastic syndrome.
Haematologica
; 103(4): 614-625, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29326122
4.
ConBind: motif-aware cross-species alignment for the identification of functional transcription factor binding sites.
Nucleic Acids Res
; 44(8): e72, 2016 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26721389
5.
Single-cell analyses of regulatory network perturbations using enhancer-targeting TALEs suggest novel roles for PU.1 during haematopoietic specification.
Development
; 141(20): 4018-30, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25252941
6.
Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner.
Haematologica
; 101(10): 1216-1227, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27390361
7.
Constrained transcription factor spacing is prevalent and important for transcriptional control of mouse blood cells.
Nucleic Acids Res
; 42(22): 13513-24, 2014 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25428352
8.
Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes.
Blood
; 122(14): e12-22, 2013 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-23974199
9.
Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia.
Blood
; 122(15): 2694-703, 2013 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-23974202
10.
Hard-wired heterogeneity in blood stem cells revealed using a dynamic regulatory network model.
Bioinformatics
; 29(13): i80-8, 2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23813012
11.
The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice.
Blood
; 120(19): 4006-17, 2012 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22932805
12.
GFI1 is required for RUNX1/ETO positive acute myeloid leukemia.
Haematologica
; 103(9): e395-e399, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29674496
13.
Dose-dependent effect of GFI1 expression in the reconstitution and the differentiation capacity of HSCs.
Front Cell Dev Biol
; 11: 866847, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37091981
14.
Structural Variants as a Basis for Targeted Therapies in Hematological Malignancies.
Front Oncol
; 9: 839, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31555592
15.
Correction: LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.
Leukemia
; 33(6): 1541, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-30837671
16.
LSD1 inhibition by tranylcypromine derivatives interferes with GFI1-mediated repression of PU.1 target genes and induces differentiation in AML.
Leukemia
; 33(6): 1411-1426, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30679800
17.
Enforced GFI1 expression impedes human and murine leukemic cell growth.
Sci Rep
; 7(1): 15720, 2017 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-29147018
18.
An experimentally validated network of nine haematopoietic transcription factors reveals mechanisms of cell state stability.
Elife
; 5: e11469, 2016 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26901438
19.
Epigenetic therapy as a novel approach for GFI136N-associated murine/human AML.
Exp Hematol
; 44(8): 713-726.e14, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27216773
20.
Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis.
Nat Cell Biol
; 15(4): 363-72, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23524953