Detalhe da pesquisa
1.
Inducing and exploiting vulnerabilities for the treatment of liver cancer.
Nature
; 574(7777): 268-272, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31578521
2.
Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes.
Gastroenterology
; 156(6): 1788-1804.e13, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30641053
3.
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers.
EMBO J
; 31(14): 3079-91, 2012 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22692129
4.
Biased competition between Lgr5 intestinal stem cells driven by oncogenic mutation induces clonal expansion.
EMBO Rep
; 15(1): 62-9, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24355609
5.
Development of Light-Activated CRISPR Using Guide RNAs with Photocleavable Protectors.
Angew Chem Int Ed Engl
; 55(40): 12440-4, 2016 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27554600
6.
Lgr5 intestinal stem cells have high telomerase activity and randomly segregate their chromosomes.
EMBO J
; 30(6): 1104-9, 2011 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21297579
7.
Occult progression by Apc-deficient intestinal crypts as a target for chemoprevention.
Carcinogenesis
; 35(1): 237-46, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23996931
8.
Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse.
Cell Rep Med
; 5(3): 101471, 2024 Mar 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-38508142
9.
Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity.
PLoS One
; 17(9): e0273182, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36067171
10.
cFLIP suppression and DR5 activation sensitize senescent cancer cells to senolysis.
Nat Cancer
; 3(11): 1284-1299, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36414711
11.
Identification of NQO2 As a Protein Target in Small Molecule Modulation of Hepatocellular Function.
ACS Chem Biol
; 16(9): 1770-1778, 2021 09 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34427427
12.
Identification of Autophagy-Related Genes as Targets for Senescence Induction Using a Customizable CRISPR-Based Suicide Switch Screen.
Mol Cancer Res
; 19(10): 1613-1621, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34158393
13.
The Cancer SENESCopedia: A delineation of cancer cell senescence.
Cell Rep
; 36(4): 109441, 2021 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34320349
14.
Engineering a perfusable 3D human liver platform from iPS cells.
Lab Chip
; 16(14): 2644-53, 2016 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27296616
15.
Wnt signaling, stem cells, and cancer of the gastrointestinal tract.
Cold Spring Harb Perspect Biol
; 4(4): a007989, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22474007
16.
Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas.
Science
; 337(6095): 730-5, 2012 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22855427
17.
Slide preparation for single-cell-resolution imaging of fluorescent proteins in their three-dimensional near-native environment.
Nat Protoc
; 6(8): 1221-8, 2011 Jul 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21799490