Detalhe da pesquisa
1.
Corallopyronin A: antimicrobial discovery to preclinical development.
Nat Prod Rep
; 39(9): 1705-1720, 2022 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35730490
2.
Orientia tsutsugamushi Is Highly Susceptible to the RNA Polymerase Switch Region Inhibitor Corallopyronin A In Vitro and In Vivo.
Antimicrob Agents Chemother
; 62(4)2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29358295
3.
Chemical Glucosylation of Labile Natural Products Using a (2-Nitrophenyl)acetyl-Protected Glucosyl Acetimidate Donor.
European J Org Chem
; 2018(20-21): 2701-2706, 2018 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29937688
4.
Insights into Structure-Activity Relationships of Bacterial RNA Polymerase Inhibiting Corallopyronin Derivatives.
J Nat Prod
; 78(10): 2505-9, 2015 Oct 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26431157
5.
Corallopyronin A - a promising antibiotic for treatment of filariasis.
Int J Med Microbiol
; 304(1): 72-8, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24079981
6.
Mesoporous Silica as an Alternative Vehicle to Overcome Solubility Limitations.
Pharmaceutics
; 16(3)2024 Mar 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38543280
7.
A laboratory-based predictive pathway for the development of Neisseria gonorrhoeae high-level resistance to corallopyronin A, an inhibitor of bacterial RNA polymerase.
Microbiol Spectr
; : e0056024, 2024 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38647280
8.
The MraY Inhibitor Muraymycin D2 and Its Derivatives Induce Enlarged Cells in Obligate Intracellular Chlamydia and Wolbachia and Break the Persistence Phenotype in Chlamydia.
Antibiotics (Basel)
; 13(5)2024 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38786149
9.
The ClpP peptidase of Wolbachia endobacteria is a novel target for drug development against filarial infections.
J Antimicrob Chemother
; 68(8): 1790-800, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23584755
10.
Requirement of lipid II biosynthesis for cell division in cell wall-less Wolbachia, endobacteria of arthropods and filarial nematodes.
Int J Med Microbiol
; 303(3): 140-9, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23517690
11.
Corallopyronin A specifically targets and depletes essential obligate Wolbachia endobacteria from filarial nematodes in vivo.
J Infect Dis
; 206(2): 249-57, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22586066
12.
The RNA Polymerase Inhibitor Corallopyronin A Has a Lower Frequency of Resistance Than Rifampicin in Staphylococcus aureus.
Antibiotics (Basel)
; 11(7)2022 Jul 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35884174
13.
Pharmacokinetics and Pharmacodynamics (PK/PD) of Corallopyronin A against Methicillin-Resistant Staphylococcus aureus.
Pharmaceutics
; 15(1)2022 Dec 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-36678760
14.
In Vitro-In Vivo Relationship in Mini-Scale-Enabling Formulations of Corallopyronin A.
Pharmaceutics
; 14(8)2022 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36015283
15.
Potent In Vitro and Ex Vivo Anti-Gonococcal Activity of the RpoB Inhibitor Corallopyronin A.
mSphere
; 7(5): e0036222, 2022 Oct 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36094073
16.
Towards the sustainable discovery and development of new antibiotics.
Nat Rev Chem
; 5(10): 726-749, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37118182
17.
Towards the sustainable discovery and development of new antibiotics.
Nat Rev Chem
; 5(10): 726-749, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34426795
18.
Functional conservation of the lipid II biosynthesis pathway in the cell wall-less bacteria Chlamydia and Wolbachia: why is lipid II needed?
Mol Microbiol
; 73(5): 913-23, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19656295
19.
Corallopyronin A for short-course anti-wolbachial, macrofilaricidal treatment of filarial infections.
PLoS Negl Trop Dis
; 14(12): e0008930, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33284808
20.
Solubility and Stability Enhanced Oral Formulations for the Anti-Infective Corallopyronin A.
Pharmaceutics
; 12(11)2020 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33217948