Detalhe da pesquisa
1.
Inhibition of the glucocorticoid-activating enzyme 11ß-hydroxysteroid dehydrogenase type 1 drives concurrent 11-oxygenated androgen excess.
FASEB J
; 38(7): e23574, 2024 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38551804
2.
Metabolism of Oral Turinabol by Human Steroid Hormone-Synthesizing Cytochrome P450 Enzymes.
Drug Metab Dispos
; 44(2): 227-37, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26658226
3.
A recombinant CYP11B1 dependent Escherichia coli biocatalyst for selective cortisol production and optimization towards a preparative scale.
Microb Cell Fact
; 14: 25, 2015 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25880059
4.
A CYP21A2 based whole-cell system in Escherichia coli for the biotechnological production of premedrol.
Microb Cell Fact
; 14: 135, 2015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26374204
5.
5α-reduction of epitestosterone is catalysed by human SRD5A1 and SRD5A2 and increases androgen receptor transactivation.
J Steroid Biochem Mol Biol
; 241: 106516, 2024 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-38582131
6.
The glucocorticoid-activating enzyme 11ß-hydroxysteroid dehydrogenase type 1 catalyzes the activation of testosterone.
J Steroid Biochem Mol Biol
; 236: 106436, 2024 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38035948
7.
Classic and 11-oxygenated androgens in serum and saliva across adulthood: a cross-sectional study analyzing the impact of age, body mass index, and diurnal and menstrual cycle variation.
Eur J Endocrinol
; 188(1)2023 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36651154
8.
Tissue Glucocorticoid Metabolism in Adrenal Insufficiency: A Prospective Study of Dual-release Hydrocortisone Therapy.
J Clin Endocrinol Metab
; 108(12): 3178-3189, 2023 Nov 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37339332
9.
Architecture of androgen receptor pathways amplifying glucagon-like peptide-1 insulinotropic action in male pancreatic ß cells.
Cell Rep
; 42(5): 112529, 2023 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37200193
10.
Multi-steroid profiling by UHPLC-MS/MS with post-column infusion of ammonium fluoride.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1209: 123413, 2022 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35988498
11.
Peripheral blood mononuclear cells preferentially activate 11-oxygenated androgens.
Eur J Endocrinol
; 184(3): 353-363, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-33444228
12.
11-Oxygenated Estrogens Are a Novel Class of Human Estrogens but Do not Contribute to the Circulating Estrogen Pool.
Endocrinology
; 162(3)2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33340399
13.
Intracrine Testosterone Activation in Human Pancreatic ß-Cells Stimulates Insulin Secretion.
Diabetes
; 69(11): 2392-2399, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32855171
14.
The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1.
J Steroid Biochem Mol Biol
; 202: 105724, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32629108
15.
Adrenal-Permissive HSD3B1 Genotype-An Invisible Stimulator of Prostate Cancer Mortality.
JAMA Netw Open
; 7(3): e243402, 2024 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38506812
16.
Understanding the Role of Androgen Action in Female Adipose Tissue.
Front Horm Res
; 53: 33-49, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31499495
17.
A novel high-throughput assay for the measurement of salivary progesterone by liquid chromatography tandem mass spectrometry.
Ann Clin Biochem
; 56(1): 64-71, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29792048
18.
Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive review.
J Steroid Biochem Mol Biol
; 194: 105439, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31362062
19.
Steroid Metabolome Analysis in Disorders of Adrenal Steroid Biosynthesis and Metabolism.
Endocr Rev
; 40(6): 1605-1625, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31294783
20.
Measurement of Salivary Adrenal-Specific Androgens as Biomarkers of Therapy Control in 21-Hydroxylase Deficiency.
J Clin Endocrinol Metab
; 104(12): 6417-6429, 2019 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31361321