Detalhe da pesquisa
1.
Marine Invertebrates: A Promissory Still Unexplored Source of Inhibitors of Biomedically Relevant Metallo Aminopeptidases Belonging to the M1 and M17 Families.
Mar Drugs
; 21(5)2023 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37233473
2.
Structure-activity relationship and molecular modelling studies of quinazolinedione derivatives MMV665916 as potential antimalarial agent.
Bioorg Med Chem
; 51: 116513, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34798379
3.
Aminobenzosuberone derivatives as PfA-M1 inhibitors: Molecular recognition and antiplasmodial evaluation.
Bioorg Chem
; 98: 103750, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32182520
4.
Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases.
Molecules
; 23(10)2018 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30314342
5.
Selective inhibition of PfA-M1, over PfA-M17, by an amino-benzosuberone derivative blocks malaria parasites development in vitro and in vivo.
Malar J
; 16(1): 382, 2017 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28934959
6.
Iminosugar-Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels.
Chemistry
; 22(15): 5151-5, 2016 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26917097
7.
Exploring S1 plasticity and probing S1' subsite of mammalian aminopeptidase N/CD13 with highly potent and selective aminobenzosuberone inhibitors.
Bioorg Med Chem
; 23(13): 3192-207, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25982416
8.
Selective aminopeptidase-N (CD13) inhibitors with relevance to cancer chemotherapy.
Bioorg Med Chem
; 21(7): 2135-44, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23428964
9.
A diverted total synthesis of mycolactone analogues: an insight into Buruli ulcer toxins.
Chemistry
; 17(51): 14413-9, 2011 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22127975
10.
Biochemical evidences for M1-, M17- and M18-like aminopeptidases in marine invertebrates from Cuban coastline.
Z Naturforsch C J Biosci
; 75(11-12): 397-407, 2020 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32609656