Detalhe da pesquisa
1.
Validation of a good manufacturing practice procedure for the production of [11C]AZD4747, a CNS penetrant KRASG12c inhibitor.
J Labelled Comp Radiopharm
; 67(6): 245-249, 2024 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-38124264
2.
Glia Imaging Differentiates Multiple System Atrophy from Parkinson's Disease: A Positron Emission Tomography Study with [11 C]PBR28 and Machine Learning Analysis.
Mov Disord
; 37(1): 119-129, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34609758
3.
Simplified and accessible [18 F]F-AraG synthesis procedure for preclinical PET.
J Labelled Comp Radiopharm
; 65(10-11): 288-291, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35980801
4.
Multiple Applications of a Novel Biarsenical Imaging Probe in Fluorescence and PET Imaging of Melanoma.
Bioconjug Chem
; 32(3): 497-501, 2021 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33576604
5.
One-Pot Synthesis of 11 C-Labelled Primary Benzamides via Intermediate [11 C]Aroyl Dimethylaminopyridinium Salts.
Chemistry
; 27(34): 8689-8693, 2021 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33885193
6.
"In-loop" carbonylation-A simplified method for carbon-11 labelling of drugs and radioligands.
J Labelled Comp Radiopharm
; 63(3): 100-107, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31524295
7.
Development of a fully automated low-pressure [11 C]CO carbonylation apparatus.
J Labelled Comp Radiopharm
; 63(12): 517-522, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32588452
8.
Transition-Metal-Free Carbon Isotope Exchange of Phenyl Acetic Acids.
Angew Chem Int Ed Engl
; 59(32): 13490-13495, 2020 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32348625
9.
Visible-Light-Enabled Aminocarbonylation of Unactivated Alkyl Iodides with Stoichiometric Carbon Monoxide for Application on Late-Stage Carbon Isotope Labeling.
J Org Chem
; 84(24): 16076-16085, 2019 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-31769679
10.
Synthesis, 3 H-labelling and in vitro evaluation of a substituted dipiperidine alcohol as a potential ligand for chemokine receptor 2.
J Labelled Comp Radiopharm
; 62(6): 265-279, 2019 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30937946
11.
Late-Stage Isotopic Carbon Labeling of Pharmaceutically Relevant Cyclic Ureas Directly from CO2.
Angew Chem Int Ed Engl
; 57(31): 9744-9748, 2018 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29862657
12.
Reduction of [11 C]CO2 to [11 C]CO using solid supported zinc.
J Labelled Comp Radiopharm
; 60(13): 624-628, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28868618
13.
Integrated Strategy for Use of Positron Emission Tomography in Nonhuman Primates to Confirm Multitarget Occupancy of Novel Psychotropic Drugs: An Example with AZD3676.
J Pharmacol Exp Ther
; 358(3): 464-71, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27402278
14.
Large Variation in Brain Exposure of Reference CNS Drugs: a PET Study in Nonhuman Primates.
Int J Neuropsychopharmacol
; 18(10): pyv036, 2015 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25813017
15.
An evaluation of a high-pressure (11)CO carbonylation apparatus.
J Labelled Comp Radiopharm
; 58(5): 220-5, 2015 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25820685
16.
Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1.
Clin Cancer Res
; 30(7): 1338-1351, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37967136
17.
Identification of Novel, Selective Ataxia-Telangiectasia Mutated Kinase Inhibitors with the Ability to Penetrate the Blood-Brain Barrier: The Discovery of AZD1390.
J Med Chem
; 67(4): 3090-3111, 2024 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38306388
18.
Low background and high contrast PET imaging of amyloid-ß with [11C]AZD2995 and [11C]AZD2184 in Alzheimer's disease patients.
Eur J Nucl Med Mol Imaging
; 40(4): 580-93, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-23324871
19.
Identification of PET radiometabolites by cytochrome P450, UHPLC/Q-ToF-MS and fast radio-LC: applied to the PET radioligands [11C]flumazenil, [18F]FE-PE2I, and [11C]PBR28.
Anal Bioanal Chem
; 405(4): 1303-10, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23180082
20.
Reactive Palladium-Ligand Complexes for 11C-Carbonylation at Ambient Pressure: A Breakthrough in Carbon-11 Chemistry.
Pharmaceuticals (Basel)
; 16(7)2023 Jul 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37513867