Detalhe da pesquisa
1.
Cardioprotective properties of OMT-28, a synthetic analog of omega-3 epoxyeicosanoids.
J Biol Chem
; : 107372, 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38754781
2.
Phenylalanine hydroxylase contributes to serotonin synthesis in mice.
FASEB J
; 35(6): e21648, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33993565
3.
Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization.
Proc Natl Acad Sci U S A
; 114(36): E7545-E7553, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28827330
4.
Chiral lipidomics of monoepoxy and monohydroxy metabolites derived from long-chain polyunsaturated fatty acids.
J Lipid Res
; 60(1): 135-148, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30409844
5.
Hypoxia-reoxygenation enhances murine afferent arteriolar vasoconstriction by angiotensin II.
Am J Physiol Renal Physiol
; 314(3): F430-F438, 2018 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29070570
6.
Activation of Peroxisome Proliferator-Activated Receptor-δ as Novel Therapeutic Strategy to Prevent In-Stent Restenosis and Stent Thrombosis.
Arterioscler Thromb Vasc Biol
; 36(8): 1534-48, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27283742
7.
Role of Müller cell cytochrome P450 2c44 in murine retinal angiogenesis.
Prostaglandins Other Lipid Mediat
; 133: 93-102, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28442442
8.
Cytochrome P450-generated metabolites derived from ω-3 fatty acids attenuate neovascularization.
Proc Natl Acad Sci U S A
; 111(26): 9603-8, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24979774
9.
Vasopressin lowers renal epoxyeicosatrienoic acid levels by activating soluble epoxide hydrolase.
Am J Physiol Renal Physiol
; 311(6): F1198-F1210, 2016 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27681558
10.
Role of CYP eicosanoids in the regulation of pharyngeal pumping and food uptake in Caenorhabditis elegans.
J Lipid Res
; 56(11): 2110-23, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26399467
11.
CYP-13A12 of the nematode Caenorhabditis elegans is a PUFA-epoxygenase involved in behavioural response to reoxygenation.
Biochem J
; 464(1): 61-71, 2014 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25138176
12.
Cytochrome p450 enzymes in the bioactivation of polyunsaturated Fatty acids and their role in cardiovascular disease.
Adv Exp Med Biol
; 851: 151-87, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26002735
13.
Dietary omega-3 fatty acids modulate the eicosanoid profile in man primarily via the CYP-epoxygenase pathway.
J Lipid Res
; 55(6): 1150-64, 2014 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-24634501
14.
Role of CYP1A1 in modulating the vascular and blood pressure benefits of omega-3 polyunsaturated fatty acids.
J Pharmacol Exp Ther
; 351(3): 688-98, 2014 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25316121
15.
The biological actions of 11,12-epoxyeicosatrienoic acid in endothelial cells are specific to the R/S-enantiomer and require the G(s) protein.
J Pharmacol Exp Ther
; 350(1): 14-21, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24763066
16.
Cytochrome P450 subfamily 2J polypeptide 2 expression and circulating epoxyeicosatrienoic metabolites in preeclampsia.
Circulation
; 126(25): 2990-9, 2012 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23155181
17.
Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91(phox) to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock.
Nitric Oxide
; 33: 18-41, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23684565
18.
5,14-HEDGE, a 20-HETE mimetic, reverses hypotension and improves survival in a rodent model of septic shock: contribution of soluble epoxide hydrolase, CYP2C23, MEK1/ERK1/2/IKKß/IκB-α/NF-κB pathway, and proinflammatory cytokine formation.
Prostaglandins Other Lipid Mediat
; 102-103: 31-41, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23454652
19.
Serotonin-induced stereospecific formation and bioactivity of the eicosanoid 17,18-epoxyeicosatetraenoic acid in the regulation of pharyngeal pumping of C. elegans.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1868(5): 159304, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36914111
20.
Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease.
Clin Transl Sci
; 16(7): 1258-1271, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37177864