CAD/CAM full-mouth rehabilitation of an elderly patient: One-piece digital complete denture meets multilayered zirconia with gradient technology.

OBJECTIVE: This article highlights a CAD/CAM complete-mouth rehabilitation in an 82-year-old patient by means of a complete maxillary prosthesis and mandibular implant- and tooth-supported fixed restorations made from multilayered zirconia. CLINICAL CONSIDERATIONS: Comprehensive complete-mouth rehabilitations in elderly patients with adaptation of the occlusal vertical dimension (OVD) often present particular challenges. This applies especially when exacting functional and esthetic requirements are to be met and the treatment should not cause the patient too much effort, still ensuring the highest level of quality and efficiency and a low intervention rate. CONCLUSION: The digital approach used for the present patient allowed for an efficient treatment procedure, facilitated virtual evaluations using a face-scan, and enhanced the predictability of the prosthodontic outcome. The approach enabled some steps required in the conventional protocol to be omitted, resulting in a straightforward clinical treatment with minimal strain on the patient. CLINICAL SIGNIFICANCE: Because of the comprehensive recording of extraoral and intraoral data, for example with a facial scanner, it was possible to transfer a digital replica of the patient to the dental laboratory technician. With this protocol, many steps can be performed in the absence of the real patient.

Clinical performance of monolithic lithium disilicate hybrid abutment crowns over at least 3.5 years.

PURPOSE: Hybrid abutment crowns (HACs) made from monolithic ceramics represent an efficient option for single restorations on implants. However, long-term data are scarce. The purpose of this clinical trial was to evaluate the survival and complication rates of CAD-CAM fabricated HACs over a time period of at least 3.5 years. MATERIALS AND METHODS: Twenty-five patients with a total of 40 HACs made of monolithic lithium disilicate ceramic bonded to a titanium base CAD-CAM abutment were retrospectively evaluated. All implants and screw-retained restorations were placed and manufactured in the same department of a university hospital. Only crowns that had been in service for more than 3.5 years were included in the study. HACs were evaluated regarding technical and biological complications. Functional Implant Prosthodontic Scores (FIPS) were obtained. RESULTS: The mean observation time was 5.9 ± 1.4 years. Implant survival was 100%, and HAC survival was 97.5%. Over the observation period, one crown fracture was observed, necessitating refabricating of the restoration. Three minor biological complications were found. The overall mean FIPS score was 8.69 ± 1.12 points. CONCLUSIONS: Within the limitations of this study, monolithic screw-retained HACs milled from lithium disilicate ceramics and bonded to titanium bases appeared to be a reliable treatment option over more than 3.5 years due to their low biological and technical complication rates.

Biomechanical behavior of implants with different diameters in relation to simulated bone loss- an in vitro study.

OBJECTIVES: Bone resorption around implants could influence the resistance of the implant abutment complex (IAC). The present in vitro study aimed to assess the stability to static fatigue of implants presenting different levels of bone losses and diameters. MATERIALS AND METHODS: Ninety implants with an internal conical connection with 3 different implant diameters (3.3 mm (I33), 3.8 mm (I38), and 4.3 mm (I43)) and 3 simulated bone loss settings (1.5 mm (I_15), 3.0 mm (I_30), and 4.5 mm (I_45) (n = 10)) were embedded and standard abutments were mounted. All specimens were artificially aged (1,200,000 cycles, 50 N, simultaneous thermocycling) and underwent subsequently load-to-fracture test. For statistical analysis, Kolmogorov-Smirnov test, Kruskal-Wallis test, and Mann-Whitney U test (p < 0.05) were applied. RESULTS: All test specimens withstood the artificial aging without damage. The mean failure values were 382.1 (± 59.2) N (I3315), 347.0 (± 35.7) N (I3330), 315.9 N (± 30.9) (I3345), 531.4 (± 36.2) N (I3815), 514.5 (± 40.8) N (I3830), 477.9 (± 26.3) N (I3845), 710.1 (± 38.2) N (I4315), 697.9 (± 65.2) N (I4330), and 662.2 N (± 45.9) (I4345). The stability of the IACs decreased in all groups when bone loss inclined. Merely, the failure load values did not significantly differ among subgroups of I43. CONCLUSIONS: Larger implant diameters and minor circular bone loss around the implant lead to a higher stability of the IAC. The smaller the implant diameter was, the more the stability was affected by the circumferential bone level. CLINICAL RELEVANCE: Preserving crestal bone level is important to ensure biomechanical sustainability at implant systems with a conical interface. It seems sensible to take the effect of eventual bone loss around implants into account during implant planning processes and restorative considerations.

Atraumatic intraoral scans and virtual hybrid casts for custom implant abutments and zirconia implants: Accuracy of the workflow.

STATEMENT OF PROBLEM: Making impressions of 2-piece implants is typically associated with the repeated disassembly and reassembly of superstructures and related to soft-tissue trauma. Intraoral scanning of 1-piece zirconia implants is problematic because scan bodies are not readily available. Whether using virtual hybrid casts generated by merging intraoral scan data with the known surface geometry of abutments can solve these difficulties is not clear because data on accuracy of the workflow are sparse. PURPOSE: The purpose of this in vitro study was to evaluate the accuracy of virtual hybrid casts with respect to the impact of different gingival situations. The workflow was designed to render pointless the use of impression posts and scan bodies and avoid any displacement of the gingiva. MATERIAL AND METHODS: The mandibular right first molar in a typodont was replaced with a 2-piece titanium implant with a custom abutment and then a 1-piece zirconia implant. Three situations representing different gingival heights covering the abutments were simulated. Twelve intraoral scans were made for each situation to capture the recordable parts of the abutments, and virtual hybrid casts were constructed by superimposing and merging the intraoral scan data with the original laboratory scan data of the abutments. Hybrid casts were compared with reference data by using the root mean square error. Scan body-related and cast scan-related protocols were performed representing conventional digital workflows. Statistical analysis with the Kolmogorov-Smirnov, Kruskal-Wallis, and Mann-Whitney U tests with the Bonferroni correction was conducted with a statistical software program (α=.05). RESULTS: Deviation was low in the hybrid casts of the custom abutment when the entire abutment was recorded (6.5 µm; IQR: 3.0 µm), when the preparation margin was disguised (7.0 µm; IQR: 1.0 µm), and when half of the abutment was covered (8.0 µm; IQR: 4.0 µm). The accuracy in the 1-piece zirconia implant was 10.0 µm (IQR: 4.0 µm) when the whole surface of the abutment was visible and 12.5 µm (IQR: 6.0 µm) when the preparation margin was covered. When only half of the abutment was captured, a larger deviation of 22.0 µm (IQR: 7.0 µm) was observed. The hybrid cast concept demonstrated superior accuracy compared with protocols using scan bodies (76.0 µm; IQR: 27.0 µm) and cast scans (23.0 µm; IQR: 15.0 µm). CONCLUSIONS: Digital intraoral scanning and the generation of virtual hybrid casts provide high accuracy and are suitable for the fabrication of single-implant-supported restorations. The atraumatic procedure avoids tissue manipulation and reduces clinical effort.

Digital jaw relation recording to evaluate a new vertical dimension of occlusion using CAD/CAM-fabricated tooth-colored splints: a case report.

Pronounced defects of the dental hard tissue can be caused by different etiologic factors. Most frequently, they are associated with changes in the vertical dimension of occlusion (VDO), which may also influence the condylar positions. These defects can lead to irreversible loss of tooth structure and have dramatic functional and esthetic consequences, often requiring complex rehabilitation. In this situation, CAD/CAM-fabricated occlusal splints made of tooth-colored polycarbonate are a proven and safe pretreatment approach in terms of esthetics and function. Rebuilding lost dental hard tissue to restore the occlusion and VDO to an adequate condylar position is a prerequisite for any sustainable and functional rehabilitation. In the future, digital systems will support this complex process, customizing it and making it simpler and more precise. The DMD-System (Ignident) provides patient-specific jaw movement data to optimize the CAD/CAM workflow. This system allows real movement patterns to be digitized and analyzed for functional and potential therapeutic purposes, integrating them into the dental and laboratory workflow. In the present case, the familiar tooth-colored CAD/CAM-fabricated occlusal splint is supplemented by digital centric jaw relation recording and individual movement data.

Predictable esthetics in hybrid and resin-based CAD/CAM restorative materials: Translucency as a function of material thickness.

AIM: The CAM of esthetically pleasing monolithic dental restorations presents with specific challenges. One vital parameter to consider is the translucency of the materials. Previous studies have proven a correlation between translucency and material thickness for various all-ceramic materials. The aim of the present study was to assess and define the relationship between thickness and translucency in modern resin-based restorative materials. MATERIALS AND METHODS: Specimens fabricated from two resin nano-ceramics (Cerasmart, Lava Ultimate), a polymer-infiltrated ceramic network (Vita Enamic), and a polymethyl methacrylate (Telio CAD) were examined, representing these different material classes. For each material, 12 specimens (n = 12) were fabricated in five thicknesses (0.4, 0.7, 1.0, 1.3, and 1.6 mm; N = 240). The translucency was measured with a spectrophotometer. The total light transmittance for each specimen was calculated applying specialized software. Regression curves were fitted to the results and their coefficient of determination (R2) fit was determined. RESULTS: Logarithmic regression curves showed the best R2 approximation (Cerasmart: R2 = 0.994; Vita Enamic: R2 = 0.978; Lava Ultimate: R2 = 0.997; Telio CAD: R2 = 0.997) to the light transmission values. CONCLUSIONS: The results of the present study indicate that the translucency of resin-based materials can be calculated using a mathematic approach to estimate their optical behavior. Cerasmart, Lava Ultimate, Vita Enamic, and Telio CAD exhibit a logarithmic relationship between material thickness and translucency. By determining material-specific coefficients for this logarithmic function, the resulting translucency can be computed for any given material thickness.

Application of 3D-printed colored 3D-models for the fabrication of full ceramic restorations: A technical report.

OBJECTIVE: This paper presents a novel digital workflow that expedites and facilitates the manufacturing of high-end full-ceramic restorations based on "Print and Press"-Technology combined with 3D-printed colored 3D-models. CLINICAL CONSIDERATIONS: Despite ongoing innovations and developments in the digital workflow, the precision, and the final esthetic outcome is still limited compared with conventional press ceramics. The proposed method combines the advantages of digital scan- and design technologies with the proven conventional press-technology to accomplish high-end full-ceramic restorations. The restoration is digitally designed, the data set is 3D-printed in resin that can be burned out, subsequently conventionally embedded and pressed. Final esthetic finishing of the partial restorations is done on a 3D-printed physical colored 3D-model. CONCLUSION: The report describes synergetic effects of digital and analog procedures. 3D-printed colored 3D-models can positively support the manufacturing of full ceramic restorations regarding their optical integration. Therefore, the use of 3D-printed colored 3D-models signifies a new innovative technique with many promising application areas. CLINICAL SIGNIFICANCE: The combination of excellent clinical long-term data for pressed ceramic restorations and proven digital processes, like intraoral scanning, design, and additive manufacturing, in the dental field promise an individual workflow for predictability and excellent esthetics.

CAD/CAM-milled versus conventionally cast secondary crowns fabricated from high noble metal alloy: an in vitro study of retentive force.

AIM: To investigate retentive forces (RFs) of CAD/CAM-milled and conventionally cast secondary crowns (SCs) after artificial aging in an in vitro study. MATERIALS AND METHODS: Forty artificial premolars were manufactured and provided with 40 primary crowns (PCs) milled from a high noble metal alloy. SCs were fabricated from the same alloy. Ten SCs were produced with the help of a tactile scanning method (group A), 10 with the help of a photo-optical scan (spray; group B), 10 with the help of a photo-optical scan (acrylic dye; group C), and 10 using a conventional casting technique (group D). Cycles of separation were performed and RFs were measured at baseline and after 5,000 and 10,000 cycles. Surfaces were examined under a scanning electron microscope (SEM). Statistical analysis was conducted at a significance level of P ≤ 0.05. RESULTS: Group D showed the highest median RFs with respective interquartile ranges (IQRs) - baseline: 7.0(2.5) N; 5,000 cycles: 5.5(2.0) N; 10,000 cycles: 5.4(1.5) N compared with groups A, B, and C - baseline: 5.2(8.4)/3.4(11.3)/1.3(1.5) N; 5,000 cycles: 1.8(0.8)/2.1(1.7)/1.0(1.3) N; 10,000 cycles: 1.9(1.6)/2.4(2.5)/1.0(1.4) N, respectively. In contrast to groups A, B, and C, group D did not gain RF when RF values were compared after 5,000 and 10,000 cycles. The loss of RF between baseline (7.0 N) and after 10,000 cycles (5.4 N) was significant only for group D (P = 0.007), but not for groups A, B, and C. CONCLUSION: Both CAD/CAM-milled and conventionally cast SCs from a high noble metal alloy can provide sufficient RF after 10,000 cycles of artificial aging. However, groups A, B, and C showed constantly lower RF values compared with group D.

Predictable esthetics in all-ceramic restorations: Translucency as a function of material thickness.

BACKGROUND: The esthetic outcome of a dental restoration largely depends on the translucency of the materials used, especially for monolithic restorations. Research has been published reporting a correlation between translucency and material thickness. However, no mathematical formula has been described yet. The aim of the present study was to determine the mathematical relationship between material thickness and translucency of three dental ceramic materials. MATERIAL AND METHODS: Three representative all-ceramic materials were taken out of the group of silicate ceramics (IPS Empress CAD LT), lithium X-silicate ceramics (IPS e.max CAD LT), and oxide ceramics (Lava Plus HT). Sixty specimens with five different thicknesses (0.4, 0.7, 1.0, 1.3, and 1.6 mm; N = 60, n = 12) were produced out of each ceramic (N = 180). A spectrophotometer was used to measure the transmittance coefficient tc[%] for each wavelength within the visible light spectrum, and the total light transmittance (T%) was calculated for each specimen. Linear, exponential, and logarithmic regression curves were fitted to the results. RESULTS: The logarithmic regression curves exhibited the best correlation (R2; IPS Empress CAD LT, R2 = 0.996; IPS e.max CAD LT, R2 = 0.987; Lava Plus HT, R2 = 0.907) to the transmittance values. CONCLUSION: Within the limitations of the present study, the transmittance behavior of silicate ceramics, lithium-X-silicate ceramics, and oxide ceramics can be described by a logarithmic equation. The findings of this study therefore suggest that the optical behavior might be calculable by a mathematical approach.

High/low-volume center experience predicts outcome of AMS 800 in male stress incontinence: Results of a large middle European multicenter case series.

AIM: To analyze the influence of implantation volume of artificial sphincters (AMS 800) on outcome in a large central European multicenter cohort study. METHODS: As part of the DOMINO (Debates on Male Incontinence) project, the surgical procedures and outcomes were retrospectively analyzed in a total of 473 patients who received an artificial sphincter (AMS 800) between 2010 and 2012. Clinics that implanted at least 10 AMS 800 per year were defined as high-volume centers. RESULTS: Sixteen centers had a mean rate of 9.54 AMS 800/y of which five clinics were identified as high-volume centers. They implanted significantly more double cuffs (55% vs 12.1%; P < .001), used the perineal approach significantly more often (78% vs 67.7%; P = .003) and chose larger mean cuff sizes (4.63 cm vs 4.42 cm; P = .002). With a mean follow-up of 18 months, the revision rate was significantly higher at low-volume centers (38.5% vs 26.7%; P = .037), urethral erosion being the main reason for revision. Social continence (0-1 pads/24 h) was achieved significantly more often in high-volume centers (45.5% vs 24.2%; P = .002). CONCLUSIONS: Our study showed significantly better continence results and lower revision rates at high-volume centers, confirming earlier results that are still true in this decade. We, therefore, recommend surgery for male incontinence at qualified centers.

In vivo wear of CAD-CAM composite versus lithium disilicate full coverage first-molar restorations: a pilot study over 2 years.

OBJECTIVES: To present a digital approach to measure and compare material wear behavior of antagonistic first molar restorations made of an experimental CAD/CAM composite (COMP) and lithium disilicate ceramic (LS2) in patients with reconstructed vertical dimension of occlusion (VDO) after generalized hard tissue loss. METHODS: A total of 12 patients underwent complete full jaw rehabilitation with full occlusal coverage restorations made either of COMP or LS2. The first molar restorations (n = 48) were chosen for wear examination. At annual recall appointments, polyether impressions were taken, and resulting plaster casts were digitalized using a laboratory scanner. Mean observation period was 371 days for first and 769 days for second year. The resulting 96 datasets were analyzed by superimposition of 3-D datasets using an iterative best-fit method. Based on the superimposition data, the wear rates of the occlusal contact areas (OCAs) were calculated. RESULTS: For antagonistic restorations made of COMP, the average wear rate was 24.8 ± 13.3 µm/month, while for LS2, it was 9.5 ± 4.3 µm/month in first year, with significant differences (p < 0.0001) between the materials. In second year, monthly wear rates decreased significantly for both materials: COMP (16.2 ± 10.7 µm/month) and LS2 (5.5 ± 3.3 µm/month). Statistical comparison between wear time showed significant differences for both materials: COMP p < 0.037 and LS2 p < 0.001. A logarithmic fit (COMP R2 = 0.081; LS2 R2 = 0.038) of the data was calculated to estimate the wear progression. SIGNIFICANCE: In patients with reconstructed VDO, restorations made of LS2 show a more stable wear behavior than ones out of experimental CAD/CAM composite. In cases of complete rehabilitation, load bearing CAD/CAM-composite restorations should be critically considered for application due to their occlusal wear behavior. However, when choosing a restorative material, not only the functional occlusal stability should be taken into account but also the prospect of minimally invasive treatment with maximum preservation of natural tooth structures.

Double crown rescue concept: clinical and dental technical workflow.

For decades, double crowns in different variations have proven to be reliable attachments in removable prosthetics. Supported by teeth and implants, they provide proper retention, a considerable degree of chewing comfort, and satisfying esthetics. A wide range of applications, optimal oral hygiene capabilities, and almost unlimited expandability are just some of the advantages of double crown anchored dentures. Among other things, abutment tooth loss is a frequent complication. If an abutment tooth is lost, the secondary crown is usually filled with resin and the denture can continue to be used. However, since the loss of one or more abutment teeth changes biomechanical load ratios, a decline in stability and comfort is likely to occur as well as overloading of the remaining abutment teeth. The concept presented in this article provides for the application of computer-assisted technologies that enable the preservation of the denture according to its original design. For this purpose, a lost or hopelessly decayed tooth is replaced with an implant using digital preplanning and guided implant surgery. The original primary crown is then reattached in its exact former position applying a CAD/CAM-fabricated meso-abutment. In effect, the number of abutment teeth can be preserved, the functionality of the denture maintained with reasonable effort, and further damage prevented.

Reproducibility of a magnet-based jaw motion analysis system.

BACKGROUND: The Dental Motion Decoder system (DMS-System) is a medical device based on magnetic field technology that records mandible movements. The data can be used to program an articulator or can be directly processed over a computer-aided design (CAD) interface. The present study aimed to assess the reproducibility of this system in vitro and in vivo. MATERIAL AND METHODS: Protrusive and laterotrusive movements were simulated in vitro using an articulator (SAM SE) (Group M) and in vivo (Group P) on one test individual. Measurements were carried out in two ways: 1) Measurements were taken after initializing and referencing the system using the reference points (RPs) once, followed by 30 protrusive and laterotrusive movements (M1 and P1); and 2) Thirty individual measurements were recorded using the RPs before each measurement (M2 and P2). Values for the sagittal condylar path inclination angle (sCPIA) and the Bennett angle (BA) were exported and analyzed. The reproducibility of the system was evaluated using the standard deviations (SDs) of the measurement series (sCPIA and BA for M1, M2, P1, and P2). RESULTS: In vitro tests M1 (SD: sCPIA = 0.08 degrees; BA = 0.06 degrees) and M2 (SD: sCPIA = 0.26 degrees; BA = 0.11 degrees) showed significantly higher reproducibility (P < 0.001) compared with the in vivo measurements P1 (SD: sCPIA = 0.61 degrees; BA = 0.45 degrees) and P2 (SD: sCPIA = 1.4 degrees; BA = 0.65 degrees). CONCLUSION: Within the limitations of the present study, the deviation in vitro, representing the reproducibility of the DMD-System, is smaller than the biologic variance observed in vivo. Therefore, reliable measurements under clinical conditions can be assumed.

Retentive force of PEEK secondary crowns on zirconia primary crowns over time.

OBJECTIVES: The purpose of the present study was to evaluate the retentive forces of CAD/CAM-fabricated polyetheretherketone (PEEK) secondary crowns on zirconia primary crowns over an artificial aging period representing 10 years of clinical service and compare them to electroformed secondary crowns made from pure gold. MATERIAL AND METHODS: Implant-supported zirconia primary crowns (N = 20) were CAD/CAM milled and provided either with electroformed secondary crowns (group ZE; N = 10) or CAD/CAM-fabricated PEEK secondary crowns (group ZP; N = 10). All secondary crowns were attached to a casted tertiary structure to ensure adequate stability. A universal testing machine was used to determine the retentive force values at baseline and after 1, 3, 5, and 10 years of simulated aging in the presence of artificial saliva. Data were analyzed applying Kolmogorov-Smirnov, Kruskal-Wallis, and Mann-Whitney U test. Level of significance was set at p < 0.05. RESULTS: Retentive forces were not different for the groups ZE and ZP at baseline (median ZE 2.85 N; ZP 2.8 N; p ≤ 0.218). Because retentive force values changed significantly over simulation time for group ZE (Kruskal-Wallis; p ≤ 0.028), the values between the test groups ZE and ZP differed significantly (Mann-Whitney U) at 5 years (ZE 3.03 N; ZP 2.76 N; p ≤ 0.003) and 10 years (ZE 3.1 N; ZP 2.78 N; p ≤ 0.011). CONCLUSIONS: PEEK secondary crowns exhibit stable retentive force values over 10 years of simulated aging showing no signs of deterioration while the retentive force values of electroformed secondary crowns increase over time. CLINICAL RELEVANCE: PEEK might be a suitable alternative to proven metallic materials for the fabrication of secondary crowns.

Interdisciplinary full-mouth rehabilitation for redefining esthetics, function, and orofacial harmony.

OBJECTIVE: In severe congenital or acquired orofacial anomalies, both dental esthetics and function are usually compromised. In particular, the esthetic ideas of the final desired appearance may differ from patient to patient, as the human esthetic sensibility differs significantly. Especially in complex cases, digital technology today offers outstanding improvements and simplifications in craniomaxillofacial surgical and prosthetic treatments, leading to a wide range of planning and pretreatment options. CLINICAL CONSIDERATIONS: This case report describes a patient-oriented interdisciplinary craniomaxillofacial surgical and prosthetic treatment with noninvasive tooth-colored splints, a Le Fort I osteotomy, and a full-mouth rehabilitation to meet the patient's demand for better function as well as orofacial esthetics and harmony. CONCLUSIONS: By means of the digitally planned Le Fort I intervention and completion of the prosthetic rehabilitation, it was possible to optimize esthetics and facial harmony. CLINICAL SIGNIFICANCE: In complex cases, digital technology today offers outstanding improvements and simplifications in craniomaxillofacial surgery and prosthetic treatments, leading to a wide range of planning and pretreatment options. Computer-aided design/computer-aided manufacturing technology enables the fabrication of tooth-colored flexible polycarbonate splints that offer a noninvasive, removable, functional, and esthetic solution. In intricate cases involving craniomaxillofacial anomalies, often together with necessary orofacial surgeries or prosthetic treatments due to moderate to severe tooth wear, such digital preprosthetic treatment and planning options represent an important enhancement with more predictable results.

Computable translucency as a function of thickness in a multi-layered zirconia.

STATEMENT OF PROBLEM: Determining the relationship between variable thicknesses and the translucency of dental ceramics is essential for optimizing esthetics in different clinical situations. PURPOSE: The purpose of this in vitro study was to analyze the relationship between layer thickness and translucency of 2 multi-layered monolithic zirconia materials and to develop an equation by which the grade of translucency can be calculated dependent on the materials' layer thicknesses in advance. MATERIAL AND METHODS: Two semisintered multi-layered zirconia blanks, namely KATANA Zirconia Super Translucent Multi-Layered Disk (Noritake Dental Supply Co, Ltd) and Zirconia Ultra Translucent Multi-Layered Disk (UTML) (Noritake Dental Supply Co, Ltd), were sectioned (N=96) to separate the 4 layers (n=12 per layer): enamel layer, transition layer 1, transition layer 2, body layer. All specimens were sintered in a furnace (M2 Plus; Thermo-Star) at 1500°C for 2 hours and automatically polished under water cooling up to P2400 for the thicknesses of 1.6, 1.3, 1.0, 0.7, and 0.4 mm. Transmittance of visible light was measured using a spectrophotometer (Lambda 35; Perkin Elmer). Data were analyzed using the Kolmogorov-Smirnov, 2-way ANOVA, and Scheffé post hoc tests (α=.01) and curve fitting. RESULTS: Analyzing the fitting of the values of the 8 material groups to the linear, exponential, and logarithmic curves, 7 of the 8 groups (not UTML body layer) fitted the most (R-square value closer to 1.0) to the logarithmic curve. Constants were obtained from the distance to the x-axis and the curvature. CONCLUSIONS: The methodology of this study provided the materials' specific constants a and b by analyzing the translucency behavior of KATANA Super Translucent Multi-Layered Disk and Ultra Translucent Multi-Layered Disk in different thicknesses, allowing further translucency calculation by applying the developed formula and the constants.

Digital Tissue Preservation Concept: A Workflow for Guided Immediate Implant Placement and Restoration.

The digital workflow presented here allows for fabrication and placement of a definitive custom abutment at the time of tooth extraction and guided immediate implant placement, thus preserving soft tissue anatomy. Since abutment design was based on the shape of the original tooth, it represented a de facto emergence-analog that provided ideal soft tissue support. The approach of superposing and merging of custom abutment design data with data captured intraorally after abutment placement enabled a digital impression without gingival displacement and associated trauma. The generated data facilitated the fabrication of a precisely fitting restoration concurrent with the implant healing period.

The AdVance and AdVanceXP male sling in urinary incontinence: is there a difference?

PURPOSE: To compare the efficacy and perioperative complications of the AdVanceXP with the original AdVance male sling. METHODS: We retrospectively enrolled 109 patients with an AdVance and 185 patients with an AdVanceXP male sling. The baseline characteristics and complication rates were analyzed retrospectively. Functional outcome and quality of life were evaluated prospectively by standardized, validated questionnaires. The Chi2-test for categorical and Mann-Whitney U test for continuous variables were performed to identify heterogeneity between the groups. RESULTS: Regarding operation time, there was no significant difference between the slings (p = 0.146). The complication rates were comparable in both groups except for postoperative urinary retention. This occurred significantly more often in patients with the AdVanceXP (p = 0.042). During follow-up, no differences could be identified regarding ICIQ-SF, PGI or I-QoL or number of pad usage. CONCLUSIONS: The AdVance and AdVanceXP are safe and effective treatment options for male stress urinary incontinence. However, the innovations of the AdVanceXP sling did not demonstrate a superiority over the original AdVance sling regarding functional outcome.

The Overall Survival Benefit for Patients with T1 Renal Cell Carcinoma after Nephron-Sparing Surgery Depends on Gender and Age.

Due to the recommendations in the urological guidelines to perform nephron-sparing surgery in patients with organ-confined renal cell carcinoma (RCC), the customary therapy regimen changed, but it is not well studied yet whether partial nephrectomy (PN) especially in the elderly is beneficial. From 2000 to 2015, 3,592 patients from 7 clinics undergoing surgery in RCC were identified; 2,323 had T1 tumours. We retrospectively compared the overall survival benefit of patients with T1 RCC who underwent either PN or radical nephrectomy (RN) and studied effects of age and gender. RESULTS: In T1 RCC, PN was beneficial in male patients (p = 0.0006) independent of age, especially in those men ≤75 years of age (p = 0.0005); but PN was not beneficial for female patients (p = 0.0629) regardless of age and male patients older than 75 years (p = 0.736). The OS of female patients after RN and male patients after PN is the same, regardless of age. A life expectancy of more than 45 months at least is necessary to experience an overall survival benefit after PN. CONCLUSIONS: There should be harder proven indications for PN in female patients and especially in all patients older than 75 years, particularly with regard to perioperative risk factors.

The TiLOOP® Male Sling: Did We Forejudge.

INTRODUCTION: To evaluate the safety and efficacy of the TiLOOP® male sling (pfm medical, Cologne, Germany) used in the treatment for male stress urinary incontinence (SUI). MATERIAL AND METHODS: We retrospectively evaluated a total of 34 patients with a TiLOOP® male sling. Perioperative complication rates were assessed and validated questionnaires were prospectively evaluated to assess quality of life and satisfaction rate. Outcome and complication rates were analysed by using descriptive statistics. Correlation of continence outcome and risk factors was performed with the chi-square test. A p value below 0.05 was considered statistically significant. RESULTS: The majority of patients (70.6%) were diagnosed with mild or moderate male SUI. During surgery, one instance (2.9%) of intraoperative urethral injury was observed. There were no immediate postoperative complications. The mean follow-up time was 44.6 months. An improvement of male SUI was reported by 61.9% of the patients and 38.1% reported no change according the Patient Global Impression of Improvement. The mean perineal pain score was 0.5 according to the international index of pain. CONCLUSIONS: The TiLOOP® is a safe treatment option for male SUI in our cohort with a low complication rate. However, the functional outcome of the TiLOOP® was inferior when compared to the outcome of the AdVance® male sling.