Detalhe da pesquisa
1.
The Lin28/let-7 axis regulates glucose metabolism.
Cell
; 147(1): 81-94, 2011 Sep 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21962509
2.
Transcriptomic analysis of the ocular posterior segment completes a cell atlas of the human eye.
Proc Natl Acad Sci U S A
; 120(34): e2306153120, 2023 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37566633
3.
Predicting molecular mechanisms of hereditary diseases by using their tissue-selective manifestation.
Mol Syst Biol
; 19(8): e11407, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37232043
4.
Deep Learning of the Retina Enables Phenome- and Genome-Wide Analyses of the Microvasculature.
Circulation
; 145(2): 134-150, 2022 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34743558
5.
TIE1 and TEK signalling, intraocular pressure, and primary open-angle glaucoma: a Mendelian randomization study.
J Transl Med
; 21(1): 847, 2023 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37996923
6.
Photoreceptor Layer Thinning Is an Early Biomarker for Age-Related Macular Degeneration: Epidemiologic and Genetic Evidence from UK Biobank OCT Data.
Ophthalmology
; 129(6): 694-707, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35149155
7.
Characteristics of p.Gln368Ter Myocilin Variant and Influence of Polygenic Risk on Glaucoma Penetrance in the UK Biobank.
Ophthalmology
; 128(9): 1300-1311, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33713785
8.
Widespread Allelic Heterogeneity in Complex Traits.
Am J Hum Genet
; 100(5): 789-802, 2017 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28475861
9.
Colocalization of GWAS and eQTL Signals Detects Target Genes.
Am J Hum Genet
; 99(6): 1245-1260, 2016 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27866706
10.
Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease.
PLoS Genet
; 10(7): e1004502, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25033284
11.
Systems Genetics Analysis of Genome-Wide Association Study Reveals Novel Associations Between Key Biological Processes and Coronary Artery Disease.
Arterioscler Thromb Vasc Biol
; 35(7): 1712-22, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25977570
12.
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
Nature
; 467(7317): 832-8, 2010 Oct 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20881960
13.
Identification of novel type 2 diabetes candidate genes involved in the crosstalk between the mitochondrial and the insulin signaling systems.
PLoS Genet
; 8(12): e1003046, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-23236286
14.
Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development.
Proc Natl Acad Sci U S A
; 109(35): 14035-40, 2012 Aug 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-22904188
15.
Machine Learning-Derived Baseline Visual Field Patterns Predict Future Glaucoma Onset in the Ocular Hypertension Treatment Study.
Invest Ophthalmol Vis Sci
; 65(2): 35, 2024 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38393715
16.
Polygenic Risk Scores for Glaucoma Onset in the Ocular Hypertension Treatment Study.
JAMA Ophthalmol
; 142(4): 356-363, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38483402
17.
QTL mapping of human retina DNA methylation identifies 87 gene-epigenome interactions in age-related macular degeneration.
Nat Commun
; 15(1): 1972, 2024 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38438351
18.
Integrating genetic regulation and single-cell expression with GWAS prioritizes causal genes and cell types for glaucoma.
Nat Commun
; 15(1): 396, 2024 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38195602
19.
Phenome- and genome-wide analyses of retinal optical coherence tomography images identify links between ocular and systemic health.
Sci Transl Med
; 16(731): eadg4517, 2024 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38266105
20.
Common inherited variation in mitochondrial genes is not enriched for associations with type 2 diabetes or related glycemic traits.
PLoS Genet
; 6(8)2010 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20714348