Detalhe da pesquisa
1.
[18F]FDG and [18F]FLT positron emission tomography imaging following treatment with belinostat in human ovary cancer xenografts in mice.
BMC Cancer
; 13: 168, 2013 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23548101
2.
Single agent- and combination treatment with two targeted suicide gene therapy systems is effective in chemoresistant small cell lung cancer cells.
J Gene Med
; 14(7): 445-58, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22576955
3.
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
Nature
; 444(7119): 633-7, 2006 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-17136093
4.
53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer.
Nat Cell Biol
; 4(12): 998-1002, 2002 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-12447382
5.
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis.
Nature
; 434(7035): 864-70, 2005 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-15829956
6.
Proteomic profiling of human colon cancer cells treated with the histone deacetylase inhibitor belinostat.
Electrophoresis
; 31(16): 2714-21, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20717991
7.
Target enzyme mutations are the molecular basis for resistance towards pharmacological inhibition of nicotinamide phosphoribosyltransferase.
BMC Cancer
; 10: 677, 2010 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-21144000
8.
Histone deacetylase 1, 2, 6 and acetylated histone H4 in B- and T-cell lymphomas.
Histopathology
; 54(6): 688-98, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19438744
9.
Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts.
Anticancer Drugs
; 20(8): 682-92, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19606018
10.
Evaluation of the topoisomerase II-inactive bisdioxopiperazine ICRF-161 as a protectant against doxorubicin-induced cardiomyopathy.
Toxicology
; 255(1-2): 72-9, 2009 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-19010377
11.
Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors.
Biochem J
; 409(2): 581-9, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17868033
12.
Anthracycline extravasation: a comprehensive review of experimental and clinical treatments.
Tumori
; 95(3): 273-82, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19688963
13.
Differential effects of class I isoform histone deacetylase depletion and enzymatic inhibition by belinostat or valproic acid in HeLa cells.
Mol Cancer
; 7: 70, 2008 Sep 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18789133
14.
Anticancer agent CHS-828 inhibits cellular synthesis of NAD.
Biochem Biophys Res Commun
; 367(4): 799-804, 2008 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-18201551
15.
Monitoring the effect of belinostat in solid tumors by H4 acetylation.
APMIS
; 116(5): 382-92, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18452428
16.
Photocarcinogenesis of topical tazarotene and isotretinoin alone and in combination with valproic acid in hairless mice.
Exp Dermatol
; 17(11): 972-4, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18616577
17.
Plasma and cerebrospinal fluid pharmacokinetics of the histone deacetylase inhibitor, belinostat (PXD101), in non-human primates.
Cancer Chemother Pharmacol
; 62(3): 433-7, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17960383
18.
Inhibition of human Chk1 causes increased initiation of DNA replication, phosphorylation of ATR targets, and DNA breakage.
Mol Cell Biol
; 25(9): 3553-62, 2005 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15831461
19.
Retinoblastoma pathway defects show differential ability to activate the constitutive DNA damage response in human tumorigenesis.
Cancer Res
; 66(21): 10258-63, 2006 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17079443
20.
MMP-9 is differentially expressed in primary human colorectal adenocarcinomas and their metastases.
Mol Cancer Res
; 4(5): 293-302, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16687484