Health Digital Twins with Clinical Decision Support.

This paper studies the feasibility of incorporating clinical decision support (CDS) into health digital twins (HDTs). A HDT is visualized in a web application, health data are stored in a FHIR-based electronic health record, and an Arden-Syntax-based CDS interpretation and alert service is connected. The prototype focuses on interoperability of these components. The study confirms the feasibility of CDS integration into HDTs and provides insight into possibilities for further expansion.