RESUMO
In this research work, the synthesis of Ag doped hydroxyapatite coatings for dental or orthopedic implants was performed. The main goal was to determine the influence of Ag content on the roughness and antimicrobial performance of the prepared thin films. The films were deposited on Ti6Al4V alloy by means of RF magnetron sputtering. Those coatings were characterized by X-ray diffraction (XRD) and 3D surface profilometry. The antifungal activity after 1 and 7days of culture was evaluated in the presence of Candida albicans (ATCC - 10231). The increase of Ag content increased roughness and reduced the antifungal activity. The results showed that the Ag doped hydroxyapatite coatings can be a potential solution for the improvement of the antifungal activities of Ti based alloy.
Assuntos
Antifúngicos/farmacologia , Candida albicans/efeitos dos fármacos , Materiais Revestidos Biocompatíveis/química , Durapatita/química , Prata/farmacologia , Ligas , Antifúngicos/química , Candidíase/microbiologia , Materiais Revestidos Biocompatíveis/farmacologia , Implantes Dentários , Durapatita/farmacologia , Campos Eletromagnéticos , Próteses e Implantes , Prata/análise , Prata/química , Propriedades de Superfície , Titânio/químicaRESUMO
A consecutive cohort including 1080 patients undergoing "off-pump" myocardial revascularization was reviewed. An average of 2.22 bypass/patients was performed. The death-rate during the first 30 days after surgery was 0.65%. Four cases needed cross-over to on-pump. The postoperative events were: need of inotropic drugs (2.7%), atrial fibrillation (12.4%), myocardial infarction (6.6%). The extubation was performed before the first postoperative 24 h in 91.9% of cases. The majority of patients was discharged from hospital before 8 days after surgery. Off pump coronary artery bypass surgery exhibit good results for most of the patients even if they present multiple vessel disease and high operating risk.
Assuntos
Ponte de Artéria Coronária sem Circulação Extracorpórea , Doença da Artéria Coronariana/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Cardiotônicos/administração & dosagem , Estudos de Coortes , Ponte de Artéria Coronária sem Circulação Extracorpórea/efeitos adversos , Ponte de Artéria Coronária sem Circulação Extracorpórea/métodos , Doença da Artéria Coronariana/complicações , Doença da Artéria Coronariana/mortalidade , Feminino , Humanos , Tempo de Internação , Masculino , Pessoa de Meia-Idade , Revascularização Miocárdica/métodos , Estudos Retrospectivos , Análise de Sobrevida , Resultado do TratamentoRESUMO
A consecutive series of 746 patients undergoing heart beating myocardial revascularization was reviewed. An average of 2.30 grafts/patients was performed. The rate of mortality in the first 30 postoperative days was 0.28%. Two cases had to be terminated on-pump. We used the inotropic drugs in 0.6% of cases. The postoperative events were: atrial fibrillation (12.6%), myocardial infarction (0.3%). The rate of transfusion was 7.4%. The extubation was performed in the first 24 h postoperatively in 94.7% of cases. The majority of patients (91.3%) left the hospital in the first 8 d postoperatively. Off pump coronary artery bypass grafting gives good result for the most of the patients even for those with multiple vessel disease and high operating risk.