Detalhe da pesquisa
1.
Deficiency of Aph1B/C-gamma-secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment.
Proc Natl Acad Sci U S A
; 105(28): 9775-80, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18626010
2.
An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease.
Nat Genet
; 22(1): 19-22, 1999 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-10319855
3.
Total inactivation of gamma-secretase activity in presenilin-deficient embryonic stem cells.
Nat Cell Biol
; 2(7): 461-2, 2000 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-10878813
4.
Lipoprotein receptor-related protein in brain and in cultured neurons of mice deficient in receptor-associated protein and transgenic for apolipoprotein E4 or amyloid precursor protein.
Neuroscience
; 94(1): 315-21, 1999.
Artigo
em Inglês
| MEDLINE | ID: mdl-10613521
5.
The human and mouse genes coding for the alpha 2MR-associated protein.
Ann N Y Acad Sci
; 737: 504-5, 1994 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-7944154
6.
Structure and targeting in ES cells of the gene coding for mouse alpha 2-macroglobulin.
Ann N Y Acad Sci
; 737: 500-1, 1994 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-7524431
7.
Molecular analysis of the human and mouse alpha 2M family.
Ann N Y Acad Sci
; 737: 163-71, 1994 Sep 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-7524394
8.
alpha2-macroglobulin- and murinoglobulin-1- deficient mice. A mouse model for acute pancreatitis.
Am J Pathol
; 155(3): 983-93, 1999 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-10487856
9.
Analysis of expression of genes involved in apolipoprotein E-based lipoprotein metabolism in pregnant mice deficient in the receptor-associated protein, the low density lipoprotein receptor, or apolipoprotein E.
Biol Reprod
; 61(5): 1216-25, 1999 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-10529267
10.
Targeted inactivation of the mouse alpha 2-macroglobulin gene.
J Biol Chem
; 270(34): 19778-85, 1995 Aug 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-7544347
11.
Processing of beta-secretase by furin and other members of the proprotein convertase family.
J Biol Chem
; 276(6): 4211-7, 2001 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-11071887
12.
Structure of the gene (LRP1) coding for the human alpha 2-macroglobulin receptor lipoprotein receptor-related protein.
Genomics
; 24(1): 78-89, 1994 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-7534747
13.
Cloning, characterization, and chromosomal localization to 4p16 of the human gene (LRPAP1) coding for the alpha 2-macroglobulin receptor-associated protein and structural comparison with the murine gene coding for the 44-kDa heparin-binding protein.
Genomics
; 25(2): 492-500, 1995 Jan 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-7789983
14.
Molecular cloning of the mouse gene coding for alpha 2-macroglobulin and targeting of the gene in embryonic stem cells.
Genomics
; 22(3): 519-29, 1994 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-7528166
15.
Humanization of mouse 5-hydroxytryptamine1B receptor gene by homologous recombination: in vitro and in vivo characterization.
Mol Pharmacol
; 56(1): 54-67, 1999 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-10385684
16.
Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency.
Proc Natl Acad Sci U S A
; 96(21): 11872-7, 1999 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-10518543