Detalhe da pesquisa
1.
Discovery of 1-[2-(1-methyl-1H-pyrazol-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-6-yl]-3-(pyridin-4-ylmethyl)urea as a potent NAMPT (nicotinamide phosphoribosyltransferase) activator with attenuated CYP inhibition.
Bioorg Med Chem Lett
; 43: 128048, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33887438
2.
Optimization of a urea-containing series of nicotinamide phosphoribosyltransferase (NAMPT) activators.
Bioorg Med Chem Lett
; 41: 128007, 2021 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33798699
3.
Discovery of Novel Small-Molecule Inducers of Heme Oxygenase-1 That Protect Human iPSC-Derived Cardiomyocytes from Oxidative Stress.
J Pharmacol Exp Ther
; 364(1): 87-96, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29101218
4.
Synthesis and physicochemical characterization of novel phenotypic probes targeting the nuclear factor-kappa B signaling pathway.
Beilstein J Org Chem
; 9: 900-7, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23766805
5.
Discovery and optimization of indole and 7-azaindoles as Rho kinase (ROCK) inhibitors (part-II).
Bioorg Med Chem Lett
; 21(23): 7113-8, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22018789
6.
Discovery and optimization of indoles and 7-azaindoles as Rho kinase (ROCK) inhibitors (part-I).
Bioorg Med Chem Lett
; 21(23): 7107-12, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22004718
7.
Synthesis and biological evaluation of 4-quinazolinones as Rho kinase inhibitors.
Bioorg Med Chem Lett
; 21(6): 1844-8, 2011 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21349713
8.
The development of benzimidazoles as selective rho kinase inhibitors.
Bioorg Med Chem Lett
; 20(6): 1939-43, 2010 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20167489
9.
Measurement of Pyridine Nucleotides in Biological Samples Using LC-MS/MS.
Methods Mol Biol
; 1996: 61-73, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31127548
10.
Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells.
Cancer Lett
; 449: 145-162, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30771432
11.
Benzimidazole- and benzoxazole-based inhibitors of Rho kinase.
Bioorg Med Chem Lett
; 18(24): 6390-3, 2008 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18996009
12.
Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme.
Nat Commun
; 9(1): 5145, 2018 12 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30514846
13.
Furanosteroid studies. Stereoselective synthesis of the A,B,E-ring core of wortmannin.
Org Lett
; 9(17): 3221-4, 2007 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-17655248
14.
Structure-Guided Strategy for the Development of Potent Bivalent ERK Inhibitors.
ACS Med Chem Lett
; 8(7): 726-731, 2017 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28740606
15.
Studies on the synthesis of furanosteroids. I. Viridin models.
Org Lett
; 8(18): 4125-8, 2006 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-16928090
16.
Two-step electrochemical annulation for the assembly of polycyclic systems.
Org Lett
; 4(21): 3763-5, 2002 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-12375938
17.
Identification of Inhibitors of NOD1-Induced Nuclear Factor-κB Activation.
ACS Med Chem Lett
; 2(10): 780-785, 2011 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22003428