Detalhe da pesquisa
1.
CYLD is a causative gene for frontotemporal dementia - amyotrophic lateral sclerosis.
Brain
; 143(3): 783-799, 2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32185393
2.
Amyotrophic lateral sclerosis-linked UBQLN2 mutants inhibit endoplasmic reticulum to Golgi transport, leading to Golgi fragmentation and ER stress.
Cell Mol Life Sci
; 77(19): 3859-3873, 2020 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31802140
3.
Pathogenic mutation in the ALS/FTD gene, CCNF, causes elevated Lys48-linked ubiquitylation and defective autophagy.
Cell Mol Life Sci
; 75(2): 335-354, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28852778
4.
Identification of PLP2 and RAB5C as novel TPD52 binding partners through yeast two-hybrid screening.
Mol Biol Rep
; 41(7): 4565-72, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24604726
5.
Regulation of GSK-3beta and beta-Catenin by Galphaq in HEK293T cells.
Biochem Biophys Res Commun
; 395(4): 577-82, 2010 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-20399743
6.
The Redox Activity of Protein Disulfide Isomerase Inhibits ALS Phenotypes in Cellular and Zebrafish Models.
iScience
; 23(5): 101097, 2020 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-32446203
7.
Impaired NHEJ repair in amyotrophic lateral sclerosis is associated with TDP-43 mutations.
Mol Neurodegener
; 15(1): 51, 2020 09 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32907630
8.
Motor Neuron Abnormalities Correlate with Impaired Movement in Zebrafish that Express Mutant Superoxide Dismutase 1.
Zebrafish
; 16(1): 8-14, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30300572
9.
Protein Quality Control and the Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Continuum.
Front Mol Neurosci
; 10: 119, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28539871
10.
Casein kinase II phosphorylation of cyclin F at serine 621 regulates the Lys48-ubiquitylation E3 ligase activity of the SCF(cyclin F) complex.
Open Biol
; 7(10)2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29021214
11.
Preexisting MEK1P124 mutations diminish response to BRAF inhibitors in metastatic melanoma patients.
Clin Cancer Res
; 21(1): 98-105, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25370473
12.
Increased MAPK reactivation in early resistance to dabrafenib/trametinib combination therapy of BRAF-mutant metastatic melanoma.
Nat Commun
; 5: 5694, 2014 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-25452114
13.
The formin INF2 regulates basolateral-to-apical transcytosis and lumen formation in association with Cdc42 and MAL2.
Dev Cell
; 18(5): 814-27, 2010 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20493814