Detalhe da pesquisa
1.
Assembling a Cinnamyl Pharmacophore in the C3-Position of Substituted Isatins via Microwave-Assisted Synthesis: Development of a New Class of Monoamine Oxidase-B Inhibitors for the Treatment of Parkinson's Disease.
Molecules
; 28(16)2023 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37630420
2.
Design, synthesis, and biological evaluation of novel pyrido-dipyrimidines as dual topoisomerase II/FLT3 inhibitors in leukemia cells.
Bioorg Chem
; 122: 105752, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35339926
3.
Optimization and SAR investigation of novel 2,3-dihydropyrazino[1,2-a]indole-1,4-dione derivatives as EGFR and BRAFV600E dual inhibitors with potent antiproliferative and antioxidant activities.
Bioorg Chem
; 120: 105616, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35078049
4.
Digoxin mitigates diethylnitrosamine-induced acute liver injury in mice via limiting production of inflammatory mediators.
Saudi Pharm J
; 30(3): 291-299, 2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35498227
5.
A New CDK2 Inhibitor with 3-Hydrazonoindolin-2-One Scaffold Endowed with Anti-Breast Cancer Activity: Design, Synthesis, Biological Evaluation, and In Silico Insights.
Molecules
; 26(2)2021 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33466812
6.
The selective c-Met inhibitor capmatinib offsets cisplatin-nephrotoxicity and doxorubicin-cardiotoxicity and improves their anticancer efficacies.
Toxicol Appl Pharmacol
; 398: 115018, 2020 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32333917
7.
The NEDD8-activating enzyme inhibition with MLN4924 sensitizes human cancer cells of different origins to apoptosis and necroptosis.
Arch Biochem Biophys
; 691: 108513, 2020 09 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32721435
8.
Synthesis and In Vitro Antiproliferative Activity of New 1-Phenyl-3-(4-(pyridin-3-yl)phenyl)urea Scaffold-Based Compounds.
Molecules
; 23(2)2018 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29385071
9.
Serum and aqueous humor concentrations of interleukin-27 in diabetic retinopathy patients.
Int Ophthalmol
; 38(5): 1817-1823, 2018 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28741232
10.
Nilotinib induces apoptosis and autophagic cell death of activated hepatic stellate cells via inhibition of histone deacetylases.
Biochim Biophys Acta
; 1833(8): 1992-2003, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23499874
11.
Corrigendum: Unveiling the therapeutic potential of exogenous ß-hydroxybutyrate for chronic colitis in rats: novel insights on autophagy, apoptosis, and pyroptosis.
Front Pharmacol
; 15: 1382529, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38545556
12.
Clomiphene citrate co-treatment with low dose urinary FSH versus urinary FSH for clomiphene resistant PCOS: randomized controlled trial.
J Assist Reprod Genet
; 30(11): 1477-85, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24014214
13.
Mitigation of acetaminophen-induced liver toxicity by the novel phosphatidylinositol 3-kinase inhibitor alpelisib.
Front Pharmacol
; 14: 1212771, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37608890
14.
Emerging roles of tyrosine kinases in hepatic inflammatory diseases and therapeutic opportunities.
Int Immunopharmacol
; 120: 110373, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37257270
15.
Corrigendum: Mitigation of acetaminophen-induced liver toxicity by the novel phosphatidylinositol 3-kinase inhibitor alpelisib.
Front Pharmacol
; 14: 1281416, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37745058
16.
WITHDRAWN: Vinpocetine and Lactobacillus improve fatty liver in rats via modulating the oxidative stress, inflammation, adiponectin and gut microbiome.
Life Sci
; 331: 121931, 2023 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37442416
17.
Piperidine: A Versatile Heterocyclic Ring for Developing Monoamine Oxidase Inhibitors.
ACS Omega
; 8(41): 37731-37751, 2023 Oct 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-37867639
18.
Geraniol Suppresses Oxidative Stress, Inflammation, and Interstitial Collagenase to Protect against Inflammatory Arthritis.
ACS Omega
; 8(40): 37128-37139, 2023 Oct 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37841186
19.
Design and construction of novel pyridine-pyrimidine hybrids as selective COX-2 suppressors: anti-inflammatory potential, ulcerogenic profile, molecular modeling and ADME/Tox studies.
J Biomol Struct Dyn
; : 1-14, 2023 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38153371
20.
The anticancer and EGFR-TK/CDK-9 dual inhibitory potentials of new synthetic pyranopyrazole and pyrazolone derivatives: X-ray crystallography, in vitro, and in silico mechanistic investigations.
J Biomol Struct Dyn
; 41(21): 12411-12425, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36661285