Detalhe da pesquisa
1.
Serum miR-204 is an early biomarker of type 1 diabetes-associated pancreatic beta-cell loss.
Am J Physiol Endocrinol Metab
; 317(4): E723-E730, 2019 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31408375
2.
Cytokines Regulate ß-Cell Thioredoxin-interacting Protein (TXNIP) via Distinct Mechanisms and Pathways.
J Biol Chem
; 291(16): 8428-39, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26858253
3.
Altered myocardial metabolic adaptation to increased fatty acid availability in cardiomyocyte-specific CLOCK mutant mice.
Biochim Biophys Acta
; 1861(10): 1579-95, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26721420
4.
TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling.
Am J Physiol Heart Circ Physiol
; 311(1): H64-75, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27199118
5.
MicroRNA-200 is induced by thioredoxin-interacting protein and regulates Zeb1 protein signaling and beta cell apoptosis.
J Biol Chem
; 289(52): 36275-83, 2014 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25391656
6.
Thioredoxin-interacting protein promotes islet amyloid polypeptide expression through miR-124a and FoxA2.
J Biol Chem
; 289(17): 11807-11815, 2014 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-24627476
7.
FOXO1 competes with carbohydrate response element-binding protein (ChREBP) and inhibits thioredoxin-interacting protein (TXNIP) transcription in pancreatic beta cells.
J Biol Chem
; 288(32): 23194-202, 2013 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-23803610
8.
Verapamil Prevents Decline of IGF-I in Subjects With Type 1 Diabetes and Promotes ß-Cell IGF-I Signaling.
Diabetes
; 72(10): 1460-1469, 2023 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37494660
9.
What the BTBR/J mouse has taught us about diabetes and diabetic complications.
iScience
; 26(7): 107036, 2023 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37360692
10.
An approach for collaborative development of a federated biomedical knowledge graph-based question-answering system: Question-of-the-Month challenges.
J Clin Transl Sci
; 7(1): e214, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37900350
11.
A cis-element in the 5' untranslated region of the preproinsulin mRNA (ppIGE) is required for glucose regulation of proinsulin translation.
Cell Metab
; 5(3): 221-7, 2007 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-17339029
12.
Calcium channel blockers act through nuclear factor Y to control transcription of key cardiac genes.
Mol Pharmacol
; 82(3): 541-9, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22734068
13.
LDB1-mediated transcriptional complexes are sensitive to islet stress.
Islets
; 14(1): 58-68, 2022 12 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-34968409
14.
Hepatic mTORC2 Signaling Facilitates Acute Glucagon Receptor Enhancement of Insulin-Stimulated Glucose Homeostasis in Mice.
Diabetes
; 71(10): 2123-2135, 2022 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35877180
15.
Alpha Cell Thioredoxin-interacting Protein Deletion Improves Diabetes-associated Hyperglycemia and Hyperglucagonemia.
Endocrinology
; 163(11)2022 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35957590
16.
Deletion of Gdf15 Reduces ER Stress-induced Beta-cell Apoptosis and Diabetes.
Endocrinology
; 163(5)2022 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35290443
17.
Exploratory study reveals far reaching systemic and cellular effects of verapamil treatment in subjects with type 1 diabetes.
Nat Commun
; 13(1): 1159, 2022 03 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35241690
18.
Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein.
J Biol Chem
; 285(6): 3997-4005, 2010 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19959470
19.
Human Glucagon Expression Is under the Control of miR-320a.
Endocrinology
; 162(3)2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33367814
20.
Heterogeneity of Diabetes: ß-Cells, Phenotypes, and Precision Medicine: Proceedings of an International Symposium of the Canadian Institutes of Health Research's Institute of Nutrition, Metabolism and Diabetes and the U.S. National Institutes of Health's National Institute of Diabetes and Digestive and Kidney Diseases.
Diabetes
; 2021 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34957490