Detalhe da pesquisa
1.
Factor VIII trafficking to CD4+ T cells shapes its immunogenicity and requires several types of antigen-presenting cells.
Blood
; 142(3): 290-305, 2023 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37192286
2.
Suppression of anti-drug antibody formation against coagulation factor VIII by oral delivery of anti-CD3 monoclonal antibody in hemophilia A mice.
Cell Immunol
; 385: 104675, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36746071
3.
Preclinical development of plant-based oral immune modulatory therapy for haemophilia B.
Plant Biotechnol J
; 19(10): 1952-1966, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33949086
4.
Type I IFN Sensing by cDCs and CD4+ T Cell Help Are Both Requisite for Cross-Priming of AAV Capsid-Specific CD8+ T Cells.
Mol Ther
; 28(3): 758-770, 2020 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31780366
5.
Plasmacytoid and conventional dendritic cells cooperate in crosspriming AAV capsid-specific CD8+ T cells.
Blood
; 129(24): 3184-3195, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28468798
6.
Tolerance induction in hemophilia: innovation and accomplishments.
Curr Opin Hematol
; 25(5): 365-372, 2018 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29994897
7.
Expression and assembly of largest foreign protein in chloroplasts: oral delivery of human FVIII made in lettuce chloroplasts robustly suppresses inhibitor formation in haemophilia A mice.
Plant Biotechnol J
; 16(6): 1148-1160, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29106782
8.
Oral Tolerance Induction in Hemophilia B Dogs Fed with Transplastomic Lettuce.
Mol Ther
; 25(2): 512-522, 2017 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28153098
9.
Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP+CD4+ T cells.
Blood
; 125(15): 2418-27, 2015 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25700434
10.
Suppression of inhibitor formation against FVIII in a murine model of hemophilia A by oral delivery of antigens bioencapsulated in plant cells.
Blood
; 124(10): 1659-68, 2014 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24825864
11.
Oral delivery of Acid Alpha Glucosidase epitopes expressed in plant chloroplasts suppresses antibody formation in treatment of Pompe mice.
Plant Biotechnol J
; 13(8): 1023-32, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26053072
12.
Factor IX administration in the skin primes inhibitor formation and sensitizes hemophilia B mice to systemic factor IX administration.
Res Pract Thromb Haemost
; 7(8): 102248, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-38193070
13.
TLR9-Activating CpG-B ODN but Not TLR7 Agonists Triggers Antibody Formation to Factor IX in Muscle Gene Transfer.
Hum Gene Ther Methods
; 30(3): 81-92, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31140323
14.
Innovative Approaches for Immune Tolerance to Factor VIII in the Treatment of Hemophilia A.
Front Immunol
; 8: 1604, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29225598
15.
Combination therapy for inhibitor reversal in haemophilia A using monoclonal anti-CD20 and rapamycin.
Thromb Haemost
; 117(1): 33-43, 2017 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27683758
16.
Efferent projections of reuniens and rhomboid nuclei of the thalamus in the rat.
J Comp Neurol
; 499(5): 768-96, 2006 Dec 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-17048232
17.
The effect of radiation therapy on normal tissue function.
Hematol Oncol Clin North Am
; 20(1): 141-63, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16580561
18.
Serum antibody response in patients with philadelphia-chromosome positive or negative myeloproliferative neoplasms following vaccination with SARS-CoV-2 spike protein messenger RNA (mRNA) vaccines.
Leukemia
; 35(12): 3578-3580, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34741117
19.
Dynamics of antigen presentation to transgene product-specific CD4+ T cells and of Treg induction upon hepatic AAV gene transfer.
Mol Ther Methods Clin Dev
; 3: 16083, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27933310
20.
Low cost industrial production of coagulation factor IX bioencapsulated in lettuce cells for oral tolerance induction in hemophilia B.
Biomaterials
; 70: 84-93, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26302233