Pesquisa | Portal de Pesquisa da BVS

1.

Regulatory T cells mediate specific suppression by depleting peptide-MHC class II from dendritic cells.

Akkaya, Billur; Oya, Yoshihiro; Akkaya, Munir; Al Souz, Jafar; Holstein, Amanda H; Kamenyeva, Olena; Kabat, Juraj; Matsumura, Ryutaro; Dorward, David W; Glass, Deborah D; Shevach, Ethan M.

Nat Immunol ; 20(2): 218-231, 2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30643268

2.

PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells.

Stathopoulou, Chaido; Gangaplara, Arunakumar; Mallett, Grace; Flomerfelt, Francis A; Liniany, Lukasz P; Knight, David; Samsel, Leigh A; Berlinguer-Palmini, Rolando; Yim, Joshua J; Felizardo, Tania C; Eckhaus, Michael A; Edgington-Mitchell, Laura; Martinez-Fabregas, Jonathan; Zhu, Jinfang; Fowler, Daniel H; van Kasteren, Sander I; Laurence, Arian; Bogyo, Matthew; Watts, Colin; Shevach, Ethan M; Amarnath, Shoba.

Immunity ; 49(2): 247-263.e7, 2018 08 21.

Artigo em Inglês | MEDLINE | ID: mdl-30054205

3.

Polyclonally Derived Alloantigen-Specific T Regulatory Cells Exhibit Target-Specific Suppression and Capture MHC Class II from Dendritic Cells.

Oya, Yoshihiro; Tanaka, Yasuyo; Nakazawa, Takuya; Matsumura, Ryutaro; Glass, Deborah D; Nakajima, Hiroshi; Shevach, Ethan M.

J Immunol ; 212(12): 1891-1903, 2024 Jun 15.

Artigo em Inglês | MEDLINE | ID: mdl-38683146

4.

Absence of signaling into CD4âº cells via C3aR and C5aR enables autoinductive TGF-ß1 signaling and induction of Foxp3âº regulatory T cells.

Strainic, Michael G; Shevach, Ethan M; An, Fengqi; Lin, Feng; Medof, M Edward.

Nat Immunol ; 14(2): 162-71, 2013 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-23263555

5.

Disabled C3ar1/C5ar1 Signaling in Foxp3+ T Regulatory Cells Leads to TSDR Demethylation and Long-Term Stability.

Medof, M Edward; Rieder, Sadiye A; Shevach, Ethan M.

J Immunol ; 211(9): 1359-1366, 2023 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-37756526

6.

Control of Memory Phenotype T Lymphocyte Homeostasis: Role of Costimulation.

Panda, Abir K; Kim, Yong-Hee; Shevach, Ethan M.

J Immunol ; 208(4): 851-860, 2022 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-35039334

7.

William E. Paul 1936-2015.

Shevach, Ethan M; Margulies, David H.

Nat Immunol ; 16(12): 1205, 2015 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-26580498

8.

Cutting Edge: Inhibition of the Interaction of NK Inhibitory Receptors with MHC Class I Augments Antiviral and Antitumor Immunity.

Panda, Abir K; Gangaplara, Arunakumar; Buszko, Maja; Natarajan, Kannan; Boyd, Lisa F; Sharma, Suveena; Margulies, David H; Shevach, Ethan M.

J Immunol ; 205(3): 567-572, 2020 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-32601097

9.

TCR signaling fuels T(reg) cell suppressor function.

Zhu, Jinfang; Shevach, Ethan M.

Nat Immunol ; 15(11): 1002-3, 2014 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-25329180

10.

Helios Deficiency Predisposes the Differentiation of CD4⁺Foxp3^- T Cells into Peripherally Derived Regulatory T Cells.

Skadow, Mathias; Penna, Vinay R; Galant-Swafford, Jessica; Shevach, Ethan M; Thornton, Angela M.

J Immunol ; 203(2): 370-378, 2019 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-31167776

11.

Helios⁺ and Helios^- Treg subpopulations are phenotypically and functionally distinct and express dissimilar TCR repertoires.

Thornton, Angela M; Lu, Jinghua; Korty, Patricia E; Kim, Yong Chan; Martens, Craig; Sun, Peter D; Shevach, Ethan M.

Eur J Immunol ; 49(3): 398-412, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30620397

12.

Type I interferon signaling attenuates regulatory T cell function in viral infection and in the tumor microenvironment.

Gangaplara, Arunakumar; Martens, Craig; Dahlstrom, Eric; Metidji, Amina; Gokhale, Ameya S; Glass, Deborah D; Lopez-Ocasio, Maria; Baur, Rachel; Kanakabandi, Kishore; Porcella, Stephen F; Shevach, Ethan M.

PLoS Pathog ; 14(4): e1006985, 2018 04.

Artigo em Inglês | MEDLINE | ID: mdl-29672594

13.

Regulatory T cells: Master thieves of the immune system.

Akkaya, Billur; Shevach, Ethan M.

Cell Immunol ; 355: 104160, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32711171

14.

Type I IFN signaling in T regulatory cells modulates chemokine production and myeloid derived suppressor cells trafficking during EAE.

Tanwar, Shalini; Oguz, Cihan; Metidji, Amina; Dahlstrom, Eric; Barbian, Kent; Kanakabandi, Kishore; Sykora, Lydia; Shevach, Ethan M.

J Autoimmun ; 115: 102525, 2020 12.

Artigo em Inglês | MEDLINE | ID: mdl-32709481

15.

Regulatory T cells: recommendations to simplify the nomenclature.

Abbas, Abul K; Benoist, Christophe; Bluestone, Jeffrey A; Campbell, Daniel J; Ghosh, Sankar; Hori, Shohei; Jiang, Shuiping; Kuchroo, Vijay K; Mathis, Diane; Roncarolo, Maria Grazia; Rudensky, Alexander; Sakaguchi, Shimon; Shevach, Ethan M; Vignali, Dario A A; Ziegler, Steve F.

Nat Immunol ; 14(4): 307-8, 2013 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-23507634

16.

SAMHD1 Posttranscriptionally Controls the Expression of Foxp3 and Helios in Human T Regulatory Cells.

Kim, Yong Chan; Kim, Kee Kwang; Yoon, Jeongheon; Scott, David W; Shevach, Ethan M.

J Immunol ; 201(6): 1671-1680, 2018 09 15.

Artigo em Inglês | MEDLINE | ID: mdl-30104243

17.

Helios: still behind the clouds.

Thornton, Angela M; Shevach, Ethan M.

Immunology ; 158(3): 161-170, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31517385

18.

Selective deletion of Eos (Ikzf4) in T-regulatory cells leads to loss of suppressive function and development of systemic autoimmunity.

Gokhale, Ameya S; Gangaplara, Arunakumar; Lopez-Occasio, Maria; Thornton, Angela M; Shevach, Ethan M.

J Autoimmun ; 105: 102300, 2019 12.

Artigo em Inglês | MEDLINE | ID: mdl-31296356

19.

TGF-Beta to the rescue.

Shevach, Ethan M.

Immunity ; 32(5): 585-7, 2010 May 28.

Artigo em Inglês | MEDLINE | ID: mdl-20510867

20.

TCR Signaling and CD28/CTLA-4 Signaling Cooperatively Modulate T Regulatory Cell Homeostasis.

Holt, Michael P; Punkosdy, George A; Glass, Deborah D; Shevach, Ethan M.

J Immunol ; 198(4): 1503-1511, 2017 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-28053234

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