Abbreviated Breast MRI: Our Two-Year Initial Experience.

OBJECTIVE: The aim of this study was to retrospectively evaluate and present our two-year experience with abbreviated breast MRI at our academic institution as a screening tool to identify primary breast cancers. METHODS: Employing eight specialty trained breast radiologists, studies were interpreted using the BI-RADS MRI lexicon in this IRB-approved retrospective study. The protocol utilized T1-weighted, fat-saturated, pre- and post-contrast, short T1 inversion recovery images, and was completed within 10 minutes. Abbreviated breast MRI was offered to asymptomatic women of all breast densities, whose ages ranged from 24 to 90 years. Statistical analysis was performed for comparative data utilizing estimated odds ratios. RESULTS: Of 1338 patients that met inclusion criteria, 83% (1111/1338) were BI-RADS 1 or 2, 9.0% (121/1338) were BI-RADS 3, and 8% (106/1338) were categorized as either BI-RADS 4 or 5 with recommended biopsy. Biopsy of BI-RADS 4 and 5 categorized patients yielded 15 cancers for a positive predictive value (PPV) 2 of 14.2% and a PPV3 of 18.5%, with 76% (81/106) of patients undergoing the recommended biopsy. An additional cancer was detected in a BI-RADS 3 finding. All cancers detected were in women with heterogeneously dense or extremely dense breasts. Therefore, 16 cancers were detected, yielding a cancer detection rate of 12.0 per 1000. Over the next 12 to 24 months, no interval cancers were detected. CONCLUSION: Abbreviated breast MRI demonstrates a higher cancer detection rate compared with mammography only and may provide a supplemental screening method to detect breast cancers in patients with varying risk factors.

Amyloidosis of the renal pelvis presenting as flank pain.

Amyloidosis is a rare disease defined by accumulation of extracellular amyloid systemically or within a specific organ. Localized amyloidosis of the genitourinary system is extremely rare, with the predominate location being the bladder. The imaging findings are often nonspecific and mimic urothelial carcinoma. We present a 49-year-old woman with a chief complaint of flank pain. A filling defect was discovered on radiological imaging. The defect was subsequently biopsied and proven to be a primary amyloidosis of the renal pelvis. We then review the radiological findings of amyloidosis of the genitourinary system.