Detalhe da pesquisa
1.
Neuron-specific ablation of the Krabbe disease gene galactosylceramidase in mice results in neurodegeneration.
PLoS Biol
; 20(7): e3001661, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35789331
2.
Perinatal loss of galactosylceramidase in both oligodendrocytes and microglia is crucial for the pathogenesis of Krabbe disease in mice.
Mol Ther
; 2024 May 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38734898
3.
Mechanisms of demyelination and neurodegeneration in globoid cell leukodystrophy.
Glia
; 69(10): 2309-2331, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33851745
4.
Altered Trafficking and Processing of GALC Mutants Correlates with Globoid Cell Leukodystrophy Severity.
J Neurosci
; 36(6): 1858-70, 2016 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26865610
5.
Metabolic profiling reveals biochemical pathways and potential biomarkers associated with the pathogenesis of Krabbe disease.
J Neurosci Res
; 94(11): 1094-107, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27638595
6.
Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via Gαs/Gαq-mediated protein kinases A/C.
Proc Natl Acad Sci U S A
; 110(47): 19101-6, 2013 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-24191038
7.
Lysosomal Functions in Glia Associated with Neurodegeneration.
Biomolecules
; 11(3)2021 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33803137
8.
Dicer ablation in oligodendrocytes provokes neuronal impairment in mice.
Ann Neurol
; 66(6): 843-57, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20035504
9.
Pre-clinical Mouse Models of Neurodegenerative Lysosomal Storage Diseases.
Front Mol Biosci
; 7: 57, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32351971
10.
Brainstem development requires galactosylceramidase and is critical for pathogenesis in a model of Krabbe disease.
Nat Commun
; 11(1): 5356, 2020 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33097716
11.
Macrophages Expressing GALC Improve Peripheral Krabbe Disease by a Mechanism Independent of Cross-Correction.
Neuron
; 107(1): 65-81.e9, 2020 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32375064
12.
VDUP1 mediates nuclear export of HIF1alpha via CRM1-dependent pathway.
Biochim Biophys Acta
; 1783(5): 838-48, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18062927
13.
TXNIP regulates germinal center generation by suppressing BCL-6 expression.
Immunol Lett
; 129(2): 78-84, 2010 Apr 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-20156484
14.
N-terminal extension of canine glutamine synthetase created by splicing alters its enzymatic property.
J Biol Chem
; 279(2): 1184-90, 2004 Jan 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-14583610
15.
A splice variant acquiring an extra transcript leader region decreases the translation of glutamine synthetase gene.
Biochem J
; 374(Pt 1): 175-84, 2003 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12749766
16.
Ribose utilization with an excess of mutarotase causes cell death due to accumulation of methylglyoxal.
J Bacteriol
; 186(21): 7229-35, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15489434