Detalhe da pesquisa
1.
A chemoproteomic portrait of the oncometabolite fumarate.
Nat Chem Biol
; 15(4): 391-400, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718813
2.
Identifying the functional contribution of the defatty-acylase activity of SIRT6.
Nat Chem Biol
; 12(8): 614-20, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27322069
3.
Defining Metabolic and Nonmetabolic Regulation of Histone Acetylation by NSAID Chemotypes.
Mol Pharm
; 15(3): 729-736, 2018 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29240439
4.
Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe.
J Am Chem Soc
; 136(15): 5656-63, 2014 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24660829
5.
Methotrexate-based PROTACs as DHFR-specific chemical probes.
Cell Chem Biol
; 31(2): 221-233.e14, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37875111
6.
Mitoribosome sensitivity to HSP70 inhibition uncovers metabolic liabilities of castration-resistant prostate cancer.
PNAS Nexus
; 2(4): pgad115, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37091547
7.
Nonspecific membrane bilayer perturbations by ivermectin underlie SARS-CoV-2 in vitro activity.
bioRxiv
; 2023 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961094
8.
Reference compounds for characterizing cellular injury in high-content cellular morphology assays.
Nat Commun
; 14(1): 1364, 2023 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36914634
9.
SULT1A1-dependent sulfonation of alkylators is a lineage-dependent vulnerability of liver cancers.
Nat Cancer
; 4(3): 365-381, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36914816
10.
A Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19.
bioRxiv
; 2022 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35169799
11.
Suite of TMPRSS2 Assays for Screening Drug Repurposing Candidates as Potential Treatments of COVID-19.
ACS Infect Dis
; 8(6): 1191-1203, 2022 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35648838
12.
PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by NSD2 Mutation in Pediatric Acute Lymphoblastic Leukemia.
Cancer Discov
; 12(1): 186-203, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34417224
13.
Discovery of TMPRSS2 Inhibitors from Virtual Screening as a Potential Treatment of COVID-19.
ACS Pharmacol Transl Sci
; 4(3): 1124-1135, 2021 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34136758
14.
Synergistic inhibition of SARS-CoV-2 cell entry by otamixaban and covalent protease inhibitors: pre-clinical assessment of pharmacological and molecular properties.
Chem Sci
; 12(38): 12600-12609, 2021 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34703545
15.
Discovery of TMPRSS2 inhibitors from virtual screening.
bioRxiv
; 2021 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33398276
16.
Remodelin Is a Cryptic Assay Interference Chemotype That Does Not Inhibit NAT10-Dependent Cytidine Acetylation.
ACS Med Chem Lett
; 12(6): 887-892, 2021 Jun 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34141066
17.
An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19.
ACS Pharmacol Transl Sci
; 3(5): 997-1007, 2020 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33062952
18.
An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19.
bioRxiv
; 2020 Aug 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32596694
19.
An OpenData portal to share COVID-19 drug repurposing data in real time.
bioRxiv
; 2020 Jun 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32511420
20.
Dynamic Imaging of LDH Inhibition in Tumors Reveals Rapid In Vivo Metabolic Rewiring and Vulnerability to Combination Therapy.
Cell Rep
; 30(6): 1798-1810.e4, 2020 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32049011