Detalhe da pesquisa
1.
HIV-1 Nef dimers short-circuit immune receptor signaling by activating Tec-family kinases at the host cell membrane.
J Biol Chem
; 295(15): 5163-5174, 2020 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32144207
2.
Structure, function, and inhibitor targeting of HIV-1 Nef-effector kinase complexes.
J Biol Chem
; 295(44): 15158-15171, 2020 10 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32862141
3.
Cell-based Fluorescence Complementation Reveals a Role for HIV-1 Nef Protein Dimerization in AP-2 Adaptor Recruitment and CD4 Co-receptor Down-regulation.
J Biol Chem
; 292(7): 2670-2678, 2017 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28031466
4.
Synthesis and evaluation of orally active small molecule HIV-1 Nef antagonists.
Bioorg Med Chem Lett
; 26(5): 1480-1484, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26852364
5.
PROTAC-mediated degradation of HIV-1 Nef efficiently restores cell-surface CD4 and MHC-I expression and blocks HIV-1 replication.
Cell Chem Biol
; 31(4): 658-668.e14, 2024 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38508197
6.
Use of pediatric thymus to humanize mice for HIV-1 mucosal transmission.
Sci Rep
; 13(1): 17067, 2023 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37816950
7.
PROTAC-mediated Degradation of HIV-1 Nef Efficiently Restores Cell-surface CD4 and MHC-I Expression and Blocks HIV-1 Replication.
bioRxiv
; 2023 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37645900
8.
Antiretroviral Drug Discovery Targeting the HIV-1 Nef Virulence Factor.
Viruses
; 14(9)2022 09 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-36146831
9.
Dickkopf-1 (DKK-1) stimulated prostate cancer growth and metastasis and inhibited bone formation in osteoblastic bone metastases.
Prostate
; 71(6): 615-25, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-20957670
10.
Development of a brain metastatic canine prostate cancer cell line.
Prostate
; 71(12): 1251-63, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21321976
11.
The midregion, nuclear localization sequence, and C terminus of PTHrP regulate skeletal development, hematopoiesis, and survival in mice.
FASEB J
; 24(6): 1947-57, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20145205
12.
Visualization of Host Cell Kinase Activation by Viral Proteins Using GFP Fluorescence Complementation and Immunofluorescence Microscopy.
Bio Protoc
; 11(13): e4068, 2021 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34327265
13.
Parathyroid hormone-related protein promotes bone loss in T-cell leukemia as well as in solid tumors.
Leuk Lymphoma
; 61(2): 409-419, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31592701
14.
Expression of parathyroid hormone-related protein during immortalization of human peripheral blood mononuclear cells by HTLV-1: implications for transformation.
Retrovirology
; 5: 46, 2008 Jun 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-18541021
15.
Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo.
ACS Chem Biol
; 13(6): 1551-1559, 2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29763550
16.
Effector kinase coupling enables high-throughput screens for direct HIV-1 Nef antagonists with antiretroviral activity.
Chem Biol
; 20(1): 82-91, 2013 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-23352142
17.
Effects of parathyroid hormone-related protein and macrophage inflammatory protein-1α in Jurkat T-cells on tumor formation in vivo and expression of apoptosis regulatory genes in vitro.
Leuk Lymphoma
; 53(4): 688-98, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21942940
18.
Characterization of bone resorption in novel in vitro and in vivo models of oral squamous cell carcinoma.
Oral Oncol
; 48(6): 491-9, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22265717
19.
HIV-1 Nef interaction influences the ATP-binding site of the Src-family kinase, Hck.
BMC Chem Biol
; 12: 1, 2012 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22420777
20.
Osteolytic bone resorption in adult T-cell leukemia/lymphoma.
Leuk Lymphoma
; 51(4): 702-14, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20214446