Detalhe da pesquisa
1.
Exploring host epigenetic enzymes as targeted therapies for visceral leishmaniasis: in silico design and in vitro efficacy of KDM6B and ASH1L inhibitors.
Mol Divers
; 2024 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38522046
2.
Integrated machine learning-based virtual screening and biological evaluation for identification of potential inhibitors against cathepsin K.
Mol Divers
; 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38662177
3.
Identification of Potential Aldose Reductase Inhibitors Using Convolutional Neural Network-Based in Silico Screening.
J Chem Inf Model
; 63(20): 6261-6282, 2023 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-37788831
4.
Ligand-based in silico identification and biological evaluation of potential inhibitors of nicotinamide N-methyltransferase.
Mol Divers
; 27(3): 1255-1269, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35793051
5.
Recent trends in artificial intelligence-driven identification and development of anti-neurodegenerative therapeutic agents.
Mol Divers
; 25(3): 1517-1539, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-34282519
6.
ß-Sitosterol-D-Glucopyranoside Mimics Estrogenic Properties and Stimulates Glucose Utilization in Skeletal Muscle Cells.
Molecules
; 26(11)2021 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34073781
7.
Computational Design of Biologically Active Anticancer Peptides and Their Interactions with Heterogeneous POPC/POPS Lipid Membranes.
J Chem Inf Model
; 60(1): 332-341, 2020 01 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31880450
8.
Ammonium trichloro [1,2-ethanediolato-O,O']-tellurate cures experimental visceral leishmaniasis by redox modulation of Leishmania donovani trypanothione reductase and inhibiting host integrin linked PI3K/Akt pathway.
Cell Mol Life Sci
; 75(3): 563-588, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28900667
9.
Molecular, biochemical characterization and assessment of immunogenic potential of cofactor-independent phosphoglycerate mutase against Leishmania donovani: a step towards exploring novel vaccine candidate.
Parasitology
; 145(4): 508-526, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28691653
10.
Polypeptide release factors and stop codon recognition in the apicoplast and mitochondrion of Plasmodium falciparum.
Mol Microbiol
; 100(6): 1080-95, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26946524
11.
Benzofuran-dihydropyridine hybrids: A new class of potential bone anabolic agents.
Bioorg Med Chem
; 25(24): 6450-6466, 2017 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29097030
12.
Physico-chemical and in-silico analysis of a phytocystatin purified from Brassica juncea cultivar RoAgro 5444.
Biochem Cell Biol
; 94(6): 584-596, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27845561
13.
Virtual screening strategies: recent advances in the identification and design of anti-cancer agents.
Methods
; 71: 64-70, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25171960
14.
Recombinant Leishmania Rab6 (rLdRab6) is recognized by sera from visceral leishmaniasis patients.
Exp Parasitol
; 170: 135-147, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27666959
15.
Evolutionary comparison of prenylation pathway in kinetoplastid Leishmania and its sister Leptomonas.
BMC Evol Biol
; 15: 261, 2015 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26588894
16.
Homology modeling of NAD+-dependent DNA ligase of the Wolbachia endosymbiont of Brugia malayi and its drug target potential using dispiro-cycloalkanones.
Antimicrob Agents Chemother
; 59(7): 3736-47, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25845868
17.
Substrate and stereocontrolled iodocycloetherification of highly functionalized enantiomerically pure allylic alcohols: application to synthesis of cytotoxic 2-epi jaspine B and its biological evaluation.
Org Biomol Chem
; 13(30): 8241-50, 2015 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26133669
18.
Identification of Novel Inhibitors of Mycobacterium tuberculosis PknG Using Pharmacophore Based Virtual Screening, Docking, Molecular Dynamics Simulation, and Their Biological Evaluation.
J Chem Inf Model
; 55(6): 1120-9, 2015 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-25965448
19.
3D-QSAR and molecular modeling studies on 2,3-dideoxy hexenopyranosid-4-uloses as anti-tubercular agents targeting alpha-mannosidase.
Bioorg Chem
; 59: 91-6, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25727263
20.
Recycling factors for ribosome disassembly in the apicoplast and mitochondrion of Plasmodium falciparum.
Mol Microbiol
; 88(5): 891-905, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23614815