Detalhe da pesquisa
1.
Current state and future perspective of drug repurposing in malignant glioma.
Semin Cancer Biol
; 68: 92-104, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31734137
2.
Dual metabolic reprogramming by ONC201/TIC10 and 2-Deoxyglucose induces energy depletion and synergistic anti-cancer activity in glioblastoma.
Br J Cancer
; 122(8): 1146-1157, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32115576
3.
Broad targeting of resistance to apoptosis in cancer.
Semin Cancer Biol
; 35 Suppl: S78-S103, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-25936818
4.
Olanzapine inhibits proliferation, migration and anchorage-independent growth in human glioblastoma cell lines and enhances temozolomide's antiproliferative effect.
J Neurooncol
; 122(1): 21-33, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25524815
5.
Photodynamic Therapy Combined with Bcl-2/Bcl-xL Inhibition Increases the Noxa/Mcl-1 Ratio Independent of Usp9X and Synergistically Enhances Apoptosis in Glioblastoma.
Cancers (Basel)
; 13(16)2021 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-34439278
6.
17-AAG sensitized malignant glioma cells to death-receptor mediated apoptosis.
Neurobiol Dis
; 33(2): 243-9, 2009 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-19027068
7.
KAAD-cyclopamine augmented TRAIL-mediated apoptosis in malignant glioma cells by modulating the intrinsic and extrinsic apoptotic pathway.
Neurobiol Dis
; 34(2): 259-66, 2009 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-19385057
8.
Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation.
Acta Neuropathol
; 117(4): 445-56, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19214542
9.
Genistein enhances proteasomal degradation of the short isoform of FLIP in malignant glioma cells and thereby augments TRAIL-mediated apoptosis.
Neurosci Lett
; 453(2): 92-7, 2009 Apr 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19356600
10.
Bcl-2/Bcl-xL inhibition predominantly synergistically enhances the anti-neoplastic activity of a low-dose CUSP9 repurposed drug regime against glioblastoma.
Br J Pharmacol
; 176(18): 3681-3694, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31222722
11.
Mitochondrial matrix chaperone and c-myc inhibition causes enhanced lethality in glioblastoma.
Oncotarget
; 8(23): 37140-37153, 2017 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-28415755
12.
Utilization of the cellular stress response to sensitize cancer cells to TRAIL-mediated apoptosis.
Expert Opin Ther Targets
; 16(8): 801-17, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22762543