Detalhe da pesquisa
1.
Structure-function relationships of the soluble form of the antiaging protein Klotho have therapeutic implications for managing kidney disease.
J Biol Chem
; 295(10): 3115-3133, 2020 03 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32005658
2.
Development of a long acting human growth hormone analog suitable for once a week dosing.
Bioorg Med Chem Lett
; 23(2): 402-6, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23253442
3.
Genetic rearrangement during site specific integration event facilitates cell line development of a bispecific molecule.
Biotechnol Prog
; 37(4): e3158, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33891804
4.
Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation.
Sci Rep
; 11(1): 8921, 2021 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33903632
5.
Transient CHO expression platform for robust antibody production and its enhanced N-glycan sialylation on therapeutic glycoproteins.
Biotechnol Prog
; 35(1): e2724, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30299005
6.
Glyco-engineered Long Acting FGF21 Variant with Optimal Pharmaceutical and Pharmacokinetic Properties to Enable Weekly to Twice Monthly Subcutaneous Dosing.
Sci Rep
; 8(1): 4241, 2018 03 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29523796
7.
Novel synthesis and structural characterization of a high-affinity paramagnetic kinase probe for the identification of non-ATP site binders by nuclear magnetic resonance.
J Med Chem
; 53(3): 1238-49, 2010 Feb 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20038108
8.
Carbon isotope effect study on orotidine 5'-monophosphate decarboxylase: support for an anionic intermediate.
Biochemistry
; 47(2): 798-803, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18081312
9.
The effective molarity of the substrate phosphoryl group in the transition state for yeast OMP decarboxylase.
Bioorg Chem
; 33(1): 45-52, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15668182
10.
Equilibrium of formation of the 6-carbanion of UMP, a potential intermediate in the action of OMP decarboxylase.
J Am Chem Soc
; 124(47): 13986-7, 2002 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-12440884
11.
The ribosome as an entropy trap.
Proc Natl Acad Sci U S A
; 101(21): 7897-901, 2004 May 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-15141076